Search results for "From ACP Journal Club"


 
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Meta-analysis: Self-monitoring in non-insulin-treated type 2 diabetes improved HbA1c by 0.25%

A meta-analysis of randomized controlled trials of patients with non–insulin-treated type 2 diabetes found that six months of self-monitoring blood glucose reduced hemoglobin A1c levels by 0.25% more than usual care.
https://diabetes.acponline.org/archives/2012/07/13/8.htm
13 Jul 2012

DPP-4 inhibitors are less effective than metformin for reducing hemoglobin A1c

A meta-analysis of randomized controlled trials comparing dipeptidyl peptidase-4 (DPP-4) inhibitors to metformin and other drugs found that DPP-4 monotherapy is less effective.
https://diabetes.acponline.org/archives/2012/08/10/7.htm
10 Aug 2012

Gastric bypass or biliopancreatic diversion increases remission from type 2 diabetes in obese adults

A randomized controlled trial (RCT) of 60 severely obese adults with type 2 diabetes found that gastric bypass or biliopancreatic diversion increased diabetes remission more than medical therapy.
https://diabetes.acponline.org/archives/2012/08/10/6.htm
10 Aug 2012

Telemonitoring was associated with greater mortality and did not reduce hospitalizations or ED visits in high-risk elderly patients

A trial in four Minnesota primary care clinics randomized high-risk elderly patients to home telemonitoring or usual care.
https://diabetes.acponline.org/archives/2012/10/12/7.htm
12 Oct 2012

Neither n-3 fatty acid supplements nor glargine reduced CV events in patients with dysglycemia

The Outcome Reduction with an Initial Glargine Intervention trial randomized about 12,000 patients with cardiovascular risk factors and dysglycemia to basal insulin glargine or usual care and daily n-3 fatty acid supplementation or olive oil placebo.
https://diabetes.acponline.org/archives/2012/10/12/8.htm
12 Oct 2012

Review: Quality improvement strategies reduce HbA1c, LDL cholesterol, and BP in diabetes

Researchers reviewed more than 140 randomized trials of quality improvement (QI) strategies for managing adult patients with diabetes.
https://diabetes.acponline.org/archives/2012/11/09/8.htm
9 Nov 2012

Intensive BP control and/or glucose control did not reduce microvascular events in hypertensive type 2 diabetes

More than 4,000 patients with type 2 diabetes, hypertension and cardiovascular disease (CVD) or CVD risk factors were randomized to a systolic blood pressure (BP) target of less than 120 mm Hg or less than 140 mm Hg.
https://diabetes.acponline.org/archives/2012/11/09/7.htm
9 Nov 2012

Intensive glucose control reduces surrogate, but not clinical, renal outcomes in type 2 diabetes

A meta-analysis included five randomized, controlled trials (with more than 28,000 patients) comparing intensive glucose control to standard glucose control in outpatients with stable type 2 diabetes.
https://diabetes.acponline.org/archives/2012/12/14/6.htm
14 Dec 2012

Hypoglycemia was associated with increased mortality in ICU patients regardless of glucose control strategy

A post hoc analysis of the NICE-SUGAR trial that included about 6,000 ICU patients compared intensive glucose control (targeting blood glucose levels of 81 to 108 mg/dL) and conventional glucose control (targeting levels ≤180 mg/dL).
https://diabetes.acponline.org/archives/2013/02/08/6.htm
8 Feb 2013

A single screening for type 2 diabetes in high-risk adults did not reduce mortality over 10 years

A trial in the United Kingdom randomized 33 primary care practices and 20,000 of their high-risk patients to screening for diabetes or usual care.
https://diabetes.acponline.org/archives/2013/02/08/7.htm
8 Feb 2013

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