Current Issue


Individualized nutrition therapy recommended for diabetes, prediabetes

Adults with diabetes should be referred to individualized, diabetes-focused medical nutrition therapy, while overweight or obese adults with prediabetes should be referred to an intensive lifestyle intervention program and/or medical nutritional therapy, according to the consensus report from the American Diabetes Association.

Metformin associated with more long-term weight loss than lifestyle change in prediabetes patients

Other independent predictors of long-term weight loss included greater weight loss in the first year and older age, according to this follow-up analysis of the Diabetes Prevention Program.

Patients with late-onset type 1 diabetes commonly treated as having type 2 diabetes

An analysis of patients with insulin-treated diabetes found that 38% of those with late-onset type 1 diabetes did not receive insulin at diagnosis, nearly half of whom reported a type 2 diabetes diagnosis.

MKSAP quiz: Type 2 diabetes and coronary artery disease

This month's quiz asks readers to modify a medication regimen for a 60-year-old man with type 2 diabetes, coronary artery disease, hypertension, hyperlipidemia, and biliary pancreatitis.

Spotlight on stroke risk

Recent studies looked at stroke risk among patients with diabetes and the effects of hypertension treatment, acetaminophen use, gout, and obesity.

Type 1 diabetes associated with risk of both medically indicated and spontaneous preterm delivery

The likelihood of giving birth before 37 weeks was increased even in women with HbA1c levels below 6.5%, suggesting that tighter control of type 1 diabetes will not eliminate this risk, the authors of the Swedish study said.

Review: Rapid-acting analogues do not differ from regular human insulin for mortality or HbA1c in type 2 diabetes

The review shows that, contrary to specialty recommendations, there is no reason not to use regular human insulins, which are less costly than analogue insulins, said an ACP Journal Club commentary.

In type 2 diabetes with periodontitis, intensive periodontitis treatment improved glycemic control at 1 year

Putting these findings into practice may require incorporating dental professionals into diabetes care teams and training clinicians who treat patients with diabetes to recognize and assess periodontal disease and make appropriate referrals, the ACP Journal Club commentary said.

Insulin info for internists

A precourse to Internal Medicine Meeting 2019, held in Philadelphia in April, focused on diabetes and offered expert advice on insulin, among other topics.

Kidney failure, CV events lower with canagliflozin than placebo, industry study finds

The trial was stopped early after an interim safety analysis found significantly better renal and cardiovascular outcomes among type 2 diabetes patients randomized to canagliflozin than those assigned to placebo.

SGLT2 inhibitors associated with rare, life-threatening necrotizing genital infections

In the past six years, nearly three times as many cases of Fournier gangrene were reported in patients taking sodium-glucose cotransporter-2 (SGLT2) inhibitors as in the past 35 years in patients taking other antiglycemic agents.

Lower glucose levels before hospital discharge associated with readmission, death in diabetes patients

Even near-normal glucose levels on the last day of hospitalization were associated with increased risk for readmission and postdischarge mortality, and these risks increased as patients' glucose levels decreased.