Current Issue


Neurologists update guideline on treatment of painful diabetic neuropathy

The updated guideline from the American Academy of Neurology supports offering tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitors, gabapentinoids, and/or sodium channel blockers to reduce pain from diabetic neuropathy.

Association of inflammation with mortality in COVID-19 didn't differ by diabetes status

A single-center, case-control study of patients who were hospitalized with COVID-19 found a link between elevated levels of IL-6, IL-8, and interferon-γ-induced protein 10 and mortality risk, regardless of whether patients had type 2 diabetes.

Metformin use during pregnancy not associated with adverse outcomes in children

A industry-conducted cohort study in Finland found that childhood obesity, hypoglycemia, hyperglycemia, diabetes, and challenges in motor-social development did not appear to be associated with in utero exposure to metformin or metformin and insulin versus insulin alone.

MKSAP quiz: Lower extremity weakness

This month's quiz asks readers to evaluate a 58-year-old man with new left lower extremity weakness, hypothyroidism, type 2 diabetes, and alcohol use disorder.

Spotlight on cardiovascular risk in type 2 diabetes

The American Heart Association released a scientific statement on managing cardiovascular (CV) risk factors, while recent research focused on CV mortality in patients with diabetes and nonalcoholic fatty liver disease and CV outcomes in high-risk patients who take sodium-glucose cotransporter-2 inhibitors.

More metformin recalled due to nitrosamine impurity

The recall includes 33 lots of metformin hydrochloride extended-release tablets USP (750 mg) manufactured in India and distributed in the U.S.