Current Issue

Societies offer guidance on treatment of hyperglycemic crises

An updated consensus statement from several diabetes and endocrinology organizations provides recommendations on the diagnosis, treatment, and prevention of diabetic ketoacidosis and hyperglycemic hyperosmolar state.

Semaglutide associated with increased cases of optic neuropathy, study finds

An observational study suggests a potential risk of nonarteritic anterior ischemic optic neuropathy associated with semaglutide, but more research is needed to assess causality, the study authors said.

SGLT-2s, GLP-1s linked with lower hyperkalemia rate than DPP-4s

Initiating therapy with sodium-glucose cotransporter-2 (SGLT-2) inhibitors was associated with the lowest risk of hyperkalemia in a retrospective comparison with glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors.

MKSAP quiz: Poor glycemic control despite intensification

This month's quiz asks readers to evaluate a 47-year-old woman who was diagnosed with type 2 diabetes mellitus 14 months ago. Despite progressive intensification of diabetes therapy, her plasma glucose levels remain poorly controlled.

Spotlight on gut microbiota in diabetes

A forum and a narrative review summarized current knowledge about the connections between diabetes and gut microbiota, while a new study identified certain species within patients' microbiomes that could relate to diabetes.

In T1DM without CVD, the LIFE-T1D model predicted lifetime risk for CVD and non-CVD mortality

The most important implication of this new model for predicting cardiovascular disease (CVD) risk among patients with type 1 diabetes (T1DM) may be that it will motivate clinicians to initiate statin therapy in younger patients, an ACP Journal Club commentary said.

Metformin safe for use while trying to conceive, studies find

Use of metformin by fathers was not associated with risk of major congenital malformation, and mothers who continued metformin and added insulin had lower risk of losing a baby than those who switched to insulin, according to two recent studies.

Case report of insulin autoimmune syndrome

A recently published case described a patient with type 2 diabetes treated with metformin who had recurrent spontaneous hypoglycemia.