Search results for "From ACP Journal Club"


 
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Review: Evidence is inconclusive on metabolic surgery vs. medical treatment for microvascular complications in T2DM

A meta-analysis from earlier this year that compared the effects of metabolic surgery and medical treatment found 10 studies to include, only three of them randomized controlled trials.
https://diabetes.acponline.org/archives/2018/08/10/7.htm
10 Aug 2018

Two reviews analyze efficacy of newer drug classes in type 1 and type 2 diabetes

The evidence favors glucagon-like peptide 1 agonists and, particularly, sodium–glucose cotransporter 2 inhibitors for type 2 diabetes, but the benefits in type 1 diabetes remain speculative, said an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2018/08/10/8.htm
10 Aug 2018

Metformin use was linked to hospitalization for acidosis at 6 y only in patients with eGFR

The results are in accordance with guidelines and regulatory policy recommendations that have extended use of metformin to individuals with mild to moderate kidney impairment, an ACP Journal Club commentary said.
https://diabetes.acponline.org/archives/2018/11/09/6.htm
9 Nov 2018

Risk scores overestimated risk for CVD in newly diagnosed type 2 diabetes

Available risk scores are in need of recalibration but still serve as useful decision-making tools, according to an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2018/12/14/8.htm
14 Dec 2018

In diabetes with no CVD, aspirin reduced serious vascular events but increased major bleeding at 7.4 years

The results of a recent trial of aspirin for cardiovascular disease (CVD) prevention in diabetes challenge current guidelines and the opinion of many clinicians of the net benefit of the drug, according to an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2019/01/11/6.htm
11 Jan 2019

In high-risk T2DM, canagliflozin reduced CV events regardless of baseline renal function

The results of the CANVAS trial are promising for patients with type 2 diabetes mellitus (T2DM) and early chronic kidney disease, but ongoing research should provide more convincing data, said an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2019/03/08/6.htm
8 Mar 2019

In type 2 diabetes with periodontitis, intensive periodontitis treatment improved glycemic control at 1 year

Putting these findings into practice may require incorporating dental professionals into diabetes care teams and training clinicians who treat patients with diabetes to recognize and assess periodontal disease and make appropriate referrals, the ACP Journal Club commentary said.
https://diabetes.acponline.org/archives/2019/05/10/8.htm
10 May 2019

Review: Rapid-acting analogues do not differ from regular human insulin for mortality or HbA1c in type 2 diabetes

The review shows that, contrary to specialty recommendations, there is no reason not to use regular human insulins, which are less costly than analogue insulins, said an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2019/05/10/7.htm
10 May 2019

Review: Viscous fiber reduces HbA1c, fasting glucose, and insulin resistance in type 2 diabetes

An ACP Journal Club commentary recommends advising patients with type 2 diabetes who don't smoke and who take metformin to also consider increasing their soluble fiber intake by more than 10 g/d.
https://diabetes.acponline.org/archives/2019/06/14/6.htm
14 Jun 2019

In uncontrolled type 2 diabetes, adjunctive semaglutide reduced HbA1c and body weight vs sitagliptin

The trial showed that an oral glucagon-like peptide-1–receptor analogue improved glycemic control compared to a dipeptidyl peptidase 4 inhibitor, but gastrointestinal side effects and cost remain barriers to use of the former class.
https://diabetes.acponline.org/archives/2019/09/13/7.htm
13 Sep 2019

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