Search results for "From ACP Journal Club"
Mediterranean diets reduced cardiovascular events more than a low-fat diet in high-risk persons
A randomized controlled trial (RCT) in Spain included older patients with type 2 diabetes mellitus or at least three major risk factors for cardiovascular disease.
https://diabetes.acponline.org/archives/2013/07/12/7.htm
12 Jul 2013
An intensive lifestyle intervention increased remission from type 2 diabetes in overweight adults
In the randomized, controlled Look AHEAD trial, an intensive lifestyle intervention (ILI) was associated with partial remission of type 2 diabetes when compared with diabetes education and support (DES).
https://diabetes.acponline.org/archives/2013/06/14/8.htm
14 Jun 2013
Metformin reduced CV events compared with glipizide in patients with type 2 diabetes and CAD
A multicenter randomized controlled trial of Chinese patients with type 2 diabetes and coronary artery disease found that metformin reduced cardiovascular events more than glipizide at 5 years.
https://diabetes.acponline.org/archives/2013/05/10/10.htm
10 May 2013
Review: Dipeptidyl peptidase-4 inhibitors do not increase overall adverse events in type 2 diabetes
A meta-analysis included 67 randomized controlled trials comparing dipeptidyl peptidase-4 (DPP-4) inhibitors to placebo or other oral antidiabetic agents.
https://diabetes.acponline.org/archives/2013/05/10/9.htm
10 May 2013
Hypoglycemia was associated with increased mortality in ICU patients regardless of glucose control strategy
A post hoc analysis of the NICE-SUGAR trial that included about 6,000 ICU patients compared intensive glucose control (targeting blood glucose levels of 81 to 108 mg/dL) and conventional glucose control (targeting levels ≤180 mg/dL).
https://diabetes.acponline.org/archives/2013/02/08/6.htm
8 Feb 2013
A single screening for type 2 diabetes in high-risk adults did not reduce mortality over 10 years
A trial in the United Kingdom randomized 33 primary care practices and 20,000 of their high-risk patients to screening for diabetes or usual care.
https://diabetes.acponline.org/archives/2013/02/08/7.htm
8 Feb 2013
Review: Intensive blood pressure control reduces stroke, but not mortality or MI, in type 2 diabetes
A meta-analysis compared five studies (including the ACCORD trial) that treated adults with type 2 diabetes with antihypertensive therapies to achieve prespecified blood pressure targets.
https://diabetes.acponline.org/archives/2013/02/08/8.htm
8 Feb 2013
Intensive glucose control reduces surrogate, but not clinical, renal outcomes in type 2 diabetes
A meta-analysis included five randomized, controlled trials (with more than 28,000 patients) comparing intensive glucose control to standard glucose control in outpatients with stable type 2 diabetes.
https://diabetes.acponline.org/archives/2012/12/14/6.htm
14 Dec 2012
Review: Quality improvement strategies reduce HbA1c, LDL cholesterol, and BP in diabetes
Researchers reviewed more than 140 randomized trials of quality improvement (QI) strategies for managing adult patients with diabetes.
https://diabetes.acponline.org/archives/2012/11/09/8.htm
9 Nov 2012
Intensive BP control and/or glucose control did not reduce microvascular events in hypertensive type 2 diabetes
More than 4,000 patients with type 2 diabetes, hypertension and cardiovascular disease (CVD) or CVD risk factors were randomized to a systolic blood pressure (BP) target of less than 120 mm Hg or less than 140 mm Hg.
https://diabetes.acponline.org/archives/2012/11/09/7.htm
9 Nov 2012