In the News

Guaranteeing adequate carbs before postpartum oral glucose tolerance testing may not be necessary

An analysis of data from two prospective studies found no relationship between carbohydrate intake in the day or days before testing and glucose level 120 minutes after oral glucose tolerance testing.

HbA1c levels above 9% may be associated with higher dementia risk

A cohort study found higher dementia risk among type 2 diabetes patients ages 50 years and older whose HbA1c levels were usually in the 9% to 10% or 10% and above range compared to those with tighter glycemic control.

GLP-1 receptor agonists associated with better primary CV prevention vs. DPP-4 inhibitors

A retrospective study compared cardiovascular (CV) outcomes among patients adding glucagon-like peptide-1 (GLP-1) receptor agonists, sodium-glucose cotransporter-2 inhibitors, or dipeptidyl peptidase-4 (DPP-4) inhibitors to metformin, sulfonylurea, or insulin treatment alone or in combination.

MKSAP quiz: Type 2 diabetes, heart failure, and kidney disease

This month's quiz asks readers to evaluate and choose a medication for a patient with type 2 diabetes who was recently hospitalized with a myocardial infarction and heart failure.

Spotlight on weekly insulins

Pharmaceutical manufacturers recently published studies on investigational basal insulin formulations that could be taken once a week by patients with type 1 or type 2 diabetes.

Large review compares benefits, harms of drugs to treat type 2 diabetes

High-certainty evidence indicated that sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists reduce all-cause death, while finerenone probably also reduced mortality based on moderate-certainty evidence.

KDIGO provided recommendations on SGLT2 inhibitors and nonsteroidal MRAs in patients with diabetes and CKD

Sodium-glucose cotransporter-2 (SGLT2) inhibitors and nonsteroidal mineralocorticoid receptor antagonists (MRAs) are now recommended for more patients with chronic kidney disease (CKD), but data are needed on their cost-effectiveness, an ACP Journal Club commentary said.

In prediabetes, oral vitamin D reduces progression to new-onset diabetes

Other preventive treatments for patients with prediabetes may be more effective than this review found vitamin D to be, but vitamin supplementation has advantages of convenience, tolerability, availability, and cost over other options, an ACP Journal Club commentary said.

Insulin pump approved for type 1 diabetes

The FDA recently approved the MiniMed 780G System for continuous delivery of basal insulin at selectable rates and the administration of insulin boluses at a selectable amount for the management of type 1 diabetes in patients ages 7 years and older requiring insulin.