In the News

Incidence of diagnosed diabetes may be stable or declining in many countries

An analysis of 21 mostly high-income countries or jurisdictions found a downward or stable trend in clinically diagnosed diabetes incidence in recent years, but the drivers of these trends remain unknown, an accompanying editorial comment said.

No differences seen in outcomes with one-step vs. two-step gestational diabetes screening

The one-step screening process, which used a two-hour fasting glucose tolerance test, found more cases of gestational diabetes in a randomized trial, but perinatal and maternal complications did not differ.

Exercise and CBT are cost-effective for diabetes patients with depression

A study used simulation modeling to project the long-term effects of a three-month exercise and cognitive behavioral therapy (CBT) intervention for patients with type 2 diabetes and major depressive disorder. It found clear cost-effectiveness with the interventions alone or combined.

MKSAP quiz: Initiating medication therapy

This month's quiz asks readers to evaluate a 54-year-old man who was diagnosed with type 2 diabetes mellitus 3 months ago and opted for lifestyle modifications initially. His repeat hemoglobin A1c level is 7.9%, and he would like it to be less than 7%.

Spotlight on lipid treatment

Control of cholesterol levels among patients with type 2 diabetes commonly falls short of recommendations, according to two recent studies of contemporary practice in other countries.

KDIGO made 12 recommendations for managing diabetes with CKD

The kidney group's guideline supports metformin and sodium–glucose cotransporter-2 inhibitors as first-line therapies for patients with chronic kidney disease (CKD) based on consistent trial data showing their effectiveness, noted an ACP Journal Club commentary.

In T2DM, weekly insulin icodec did not differ from daily glargine for reducing HbA1c or significant/severe hypoglycemia

An ACP Journal Club commentary pointed out that use of once-weekly insulin for patients with type 2 diabetes will require more cautious dose-titration algorithms and less stringent glycemic targets to avoid hypoglycemia.

Type of insulin may affect hypoglycemia rates in older adults with type 2 diabetes, study finds

The risk of hospital visits for hypoglycemia was lower with long-acting insulin analogs versus neutral protamine Hagedorn (NPH) insulin in a retrospective study of Medicare patients.