In the News

New guideline from Endocrine Society offers guidance on lipid management

The guideline includes recommendations on the use of statins and lipid testing in type 1 and 2 diabetes, as well as other endocrine-related diseases and conditions.

One-time serum C-peptide testing detected patients misclassified as having type 1 diabetes

In a recent study, a serum C-peptide testing program resulted in reclassification of the cause of diabetes in about 7% of the cohort tested at one diabetes center in Scotland. Reclassification was most likely in those diagnosed at age 30 years or older.

In type 2 diabetes patients, lower LDL cholesterol levels after PCI associated with better outcomes

A pooled analysis of three randomized clinical trials found reductions in major adverse cardiac or cerebrovascular events after percutaneous coronary intervention (PCI) at 3.9-year follow-up only in patients with low-density lipoprotein (LDL) cholesterol levels below 70 mg/dL at one year.

MKSAP quiz: Eye exam during pregnancy

This month's quiz asks readers to determine the timing of a dilated eye examination for a pregnant woman with type 1 diabetes.

Spotlight on vitamin D

One study found more cardiovascular events in diabetic patients with vitamin D deficiency, while a trial found no effect of vitamin D supplements on cardiovascular biomarkers, and a genetic meta-analysis suggested that associations between vitamin D levels and diabetes are not causal.

SGLT2 inhibitors increase risk for diabetic ketoacidosis in type 2 diabetes

Diabetic ketoacidosis (DKA) is rare with sodium-glucose co-transporter-2 (SGLT2) inhibitors but more common than with control medications, and clinicians should be vigilant in identifying euglycemic DKA in patients on these drugs, an ACP Journal Club commentary said.

Recent KDIGO guideline focused on patients with diabetes and kidney disease

A new summary of the guideline from Kidney Disease: Improving Global Outcomes (KDIGO) highlights important points for clinicians, including recommendations about prescribing of diabetes medications.

Inpatient exercise improved outcomes in elderly type 2 diabetes patients

A single-center study randomized patients ages 75 years and older to either usual care or 20 minutes twice a day of mobility and strengthening exercises during their hospitalizations.

Group-based lifestyle intervention reduced risk of type 2 diabetes

Participants in the Norfolk Diabetes Prevention Study who underwent multiple educational group sessions that included 50-minute sessions of supervised physical activity had significantly lower odds of type 2 diabetes during a mean follow-up of two years compared to those who received usual care.

More metformin recalled due to nitrosamine impurities

Another company recalled four lots of metformin hydrochloride extended-release tablets USP (500 and 750 mg) this month due to the detection of excess levels of N-nitrosodimethylamine, a probable carcinogen.