Current Issue


Diabetes rates hold steady in latest U.S. report, rising around the world

In the U.S., 11.3% of adults have diagnosed diabetes and 4.5% have undiagnosed diabetes, a CDC report found. A global analysis found that diabetes rates are rising fastest in low- and middle-income countries in southeast Asia, south Asia, the Middle East and north Africa, and Latin America and the Caribbean.

Hypoglycemic events linked to subsequent stroke risk in diabetes

Medicare patients with diabetes who had a hypoglycemic event had higher odds of a subsequent acute ischemic stroke. Risk was highest on the day after the event and decreased with time but persisted for 30 days, the case-crossover study found.

Inhaled insulin noninferior to usual care, industry trial in type 1 diabetes finds

Patients who began using inhaled insulin were more likely to have an improvement or worsening in their HbA1c level than patients who continued their existing insulin regimens, but overall glycemic control was similar with either strategy, a randomized trial found.

MKSAP quiz: Prognosis in chronic kidney disease

This month's quiz asks readers to evaluate a 54-year-old man during a new patient visit. He has a 30-year history of type 2 diabetes mellitus and 10-year history of hypertension, as well as an estimated glomerular filtration rate that indicates chronic kidney disease.

Spotlight on GLP-1 receptor agonists

Cost and access issues were the focus of multiple recent articles about glucagon-like peptide-1 (GLP-1) and dual glucose-dependent insulinotropic polypeptide receptor agonists, while the latest research on these drug classes highlighted their clinical benefits.

Intensive BP control improved outcomes in patients with type 2 diabetes, trial finds

A composite of nonfatal stroke, nonfatal myocardial infarction, treatment or hospitalization for heart failure, or death from cardiovascular causes was significantly lower among patients treated to a blood pressure (BP) target of less than 120 mm Hg versus one below 140 mm Hg.

Risk for CVD events elevated years before type 2 diabetes diagnosis

A Danish study found that patients with type 2 diabetes had a twofold higher prevalence of cardiovascular disease (CVD) events as long as three decades before their diagnosis versus matched comparators.

In the Clinic, Ideas and Opinions address diabetes

A recent In the Clinic reviewed hyperglycemia in hospitalized patients, and an opinion article discussed misuse of race in interpretation of HbA1c levels.

After COVID-19 diagnosis, risk for incident type 2 diabetes was elevated for up to 2 y

Given that this large study found an elevated incidence of type 2 diabetes up to two years after infection, COVID-19 could now be characterized as a possible risk factor for diabetes, an ACP Journal Club commentary said.

Case reports of patients with diabetes

One recent case report described bullous pemphigoid while another described black esophagus.