https://diabetes.acponline.org/archives/2025/07/11/9.htm

Case report describes a patient with diabetic ketoacidosis

The case explains possible pathophysiologic links between cerebral venous sinus thrombosis and diabetic ketoacidosis.


A case published by Annals of Internal Medicine: Clinical Cases on July 1 described a patient with cerebral venous sinus thrombosis and diabetic ketoacidosis (DKA).

The case involves a woman in her 60s who presented with altered mental status, slurred speech, and difficulty ambulating. She had history of bilateral stroke, uncontrolled type 2 diabetes with multiple prior hospitalizations for DKA, hypertension, seizure disorder, opioid use, and hepatitis C. She was diagnosed with DKA and bilateral cerebral venous sinus thrombosis and had negative hypercoagulable, cardiac, and infectious screenings. Treatment, including fluid resuscitation, insulin, and anticoagulation, resulted in improved neurologic symptoms.