In the News

Pioglitazone use associated with reduced mortality risk, cohort analysis finds

The study did not find any consistent trend in mortality risk with increasing duration or dose, and the effect of pioglitazone on mortality was significantly modified by history of diabetes complications, chronic kidney disease, and macrovascular disease.

Benefits of gastric bypass may diminish after 5 years

Patients with type 2 diabetes who had Roux-en-Y gastric bypass surgery maintained significant, although shrinking, improvements in HbA1c compared to those receiving lifestyle and medical management.

Sociodemographic, clinical factors may influence insulin initiation in type 2 diabetes

The researchers found an inverse association between insulin initiation and age, and black and Hispanic participants were less likely to have insulin initiated compared with white participants.

MKSAP quiz: Treatment plan for obesity and diabetes

This month's quiz asks readers to evaluate a 47-year-old man who is obese and has hypertension, type 2 diabetes mellitus, and obstructive sleep apnea.

Spotlight on the value of care

One recent study found overtreatment of type 2 diabetes among elderly patients, while another looked at how many patients with diabetes would be referred to a liver specialist under proposed European guidelines.

Review compares effectiveness, cost, and safety of second-line drugs for diabetes

The review found that sulfonylureas were more cost-effective than newer agents, but an ACP Journal Club commentary stressed the importance of shared decision making in the choice of a second agent.

Prognostic value of acute-to-chronic glycemic ratio better than glycemia at admission for AMI patients

Patients' A/C glycemic ratio predicted a composite of in-hospital mortality, acute pulmonary edema, and cardiogenic shock as well as troponin I peak value, a prospective study in Italy found.