In the News

ADA's updated standards of diabetes care include recommendations for hypertension, screening high-risk youth

The American Diabetes Association (ADA)'s 2018 update also recommends that adults with type 2 diabetes and heart disease receive a medication proven to improve heart health, after lifestyle management and metformin.

Cardiovascular benefits of adding ezetimibe to statin therapy may be greater in patients with diabetes, study finds

Participants were randomized to receive either ezetimibe or placebo in addition to background simvastatin, and the subgroup of patients with diabetes was compared to those without the disease.

Individualizing glycemic control could reduce costs, increase quality-adjusted life-years

A cost-effectiveness analysis found that individualized control saved $13,547 per patient compared with uniform intensive control, primarily due to lower medication costs, and increased quality-adjusted life-years by 0.10.

MKSAP quiz: Screening in an asymptomatic patient with diabetes

This month's quiz asks readers to determine appropriate management in a patient with type 2 diabetes during a routine visit.

Spotlight on wound healing for diabetic foot ulcers

Recent trials examined the potential effects of probiotic supplements and sucrose octasulfate dressings.

Device approved to treat diabetic foot ulcers

The shock-wave system is intended to be used with standard diabetic ulcer care in patients ages 22 years and older with ulcers lasting more than 30 days.

Ertugliflozin approved as adjunct treatment for type 2 diabetes

As an adjunct to diet and exercise, the drug was approved as monotherapy and for use in fixed-dose combinations with metformin or sitagliptin.

Follow-on insulin lispro approved

The injection is approved to improve glucose control in patients ages three years and older with type 1 diabetes and in adult patients with type 2 diabetes.

Liraglutide reduced a composite renal outcome at a median 4 y in patients with type 2 diabetes and high CV risk

An ACP Journal Club commentary noted that the mechanism by which liraglutide improves renal outcomes is uncertain and that renal benefit was driven by a decrease in the surrogate outcome of macroalbuminuria, with measures of renal impairment remaining unchanged.

Exenatide did not reduce major cardiovascular outcomes in type 2 diabetes

While exenatide can be considered a second-line option for patients with type 2 diabetes and some may prefer its once-weekly dosing, those at high cardiovascular risk should receive agents with demonstrated cardiovascular benefit, according to an ACP Journal Club commentary.

Primary care-based weight-loss program led to remission of type 2 diabetes

At the end of 12 months, 36 intervention participants lost 15 kg or more, compared to no participants in the control group, and diabetes remission was associated with the amount of weight lost.