Current Issue


Metformin appears better than sulfonylureas as first-line therapy for patients with CKD

Metformin was associated with a lower risk of mortality than sulfonylureas both overall and in all categories of estimated glomerular filtration rate, the observational study found.

Impaired glucose tolerance at 1 hour may be more predictive than at 2 hours, study finds

The results highlight the potential benefit of targeting individuals with an elevated one-hour blood glucose level and, if supported by additional evidence, eventually replacing the two-hour test with a one-hour measure, the authors said.

Risk score may help predict future glycemic control after new diagnosis of diabetes

The most important predictors of the trajectory of glucose control were body mass index and levels of HbA1c and triglycerides, according to the study of registry data from the Netherlands.

MKSAP quiz: Screening for diabetes

This month's quiz asks readers to consider a 38-year-old man who expresses interest in being screened for diabetes during a periodic health maintenance visit.

Spotlight on genetic risk for diabetes

Recent studies looked at biomarkers to predict diabetes, characteristics of patients who developed type 1 diabetes during adulthood, and use of oral insulin to try to prevent type 1 diabetes.

Lifestyle modification may outperform medications over time for diabetes prevention, meta-analysis finds

Twenty-five people would need to be treated with lifestyle modification to prevent one diabetes case, according to the analysis of randomized clinical trials that evaluated lifestyle modification and medication interventions for diabetes prevention in at-risk adults.

Metformin solution recalled due to contamination

Two lots of metformin hydrochloride oral solution (Riomet), 500 mg/5 mL, were recalled due to fungal contamination, the FDA said.