Search results for "Highlights"
SGLT-2 inhibitors linked to more diabetic ketoacidosis vs. DPP-4 inhibitors or sulfonylureas
A retrospective study found that new users of sodium-glucose cotransporter-2 (SGLT-2) inhibitors developed diabetic ketoacidosis at a rate of about 6 per 1,000 person-years, compared to 4.3 or 4.5 per 1,000 person-years with dipeptidyl peptidase-4 (DPP-4) inhibitors or sulfonylureas, respectively.
https://diabetes.acponline.org/archives/2022/03/11/1.htm
11 Mar 2022
One-time serum C-peptide testing detected patients misclassified as having type 1 diabetes
In a recent study, a serum C-peptide testing program resulted in reclassification of the cause of diabetes in about 7% of the cohort tested at one diabetes center in Scotland. Reclassification was most likely in those diagnosed at age 30 years or older.
https://diabetes.acponline.org/archives/2020/11/13/2.htm
13 Nov 2020
In type 2 diabetes patients, lower LDL cholesterol levels after PCI associated with better outcomes
A pooled analysis of three randomized clinical trials found reductions in major adverse cardiac or cerebrovascular events after percutaneous coronary intervention (PCI) at 3.9-year follow-up only in patients with low-density lipoprotein (LDL) cholesterol levels below 70 mg/dL at one year.
https://diabetes.acponline.org/archives/2020/11/13/3.htm
13 Nov 2020
Tirzepatide may improve glycemic control when added to insulin glargine in type 2 diabetes
An industry-sponsored phase 3 trial found statistically significant improvements in HbA1c level among patients with type 2 diabetes who had inadequate glycemic control on insulin glargine and were randomly assigned to subcutaneous tirzepatide once weekly versus placebo.
https://diabetes.acponline.org/archives/2022/02/11/1.htm
11 Feb 2022
Studies find link between metformin and reduced COVID-19 mortality, mixed results for DPP-4 inhibitors
Prior metformin use was associated with a threefold decrease in mortality from COVID-19 in one study of patients with type 2 diabetes, while three other studies found mixed results on whether dipeptidyl peptidase-4 (DPP-4) inhibitors affect COVID-19 outcomes.
https://diabetes.acponline.org/archives/2021/02/12/2.htm
12 Feb 2021
Surgical, drug treatments have similar outcomes in patients with vitreous hemorrhage from proliferative diabetic retinopathy
A randomized trial found equivalent improvements in visual acuity at two years with either therapy but identified some differences in outcomes that could help patients and clinicians choose a treatment method.
https://diabetes.acponline.org/archives/2021/01/08/2.htm
8 Jan 2021
Neurologists update guideline on treatment of painful diabetic neuropathy
The updated guideline from the American Academy of Neurology supports offering tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitors, gabapentinoids, and/or sodium channel blockers to reduce pain from diabetic neuropathy.
https://diabetes.acponline.org/archives/2022/01/14/1.htm
14 Jan 2022
Nearly 5% of adults diagnosed with type 2 diabetes in Scotland were in remission in 2019
Compared with people who did not achieve remission, those in remission tended to be older, to have a lower HbA1c level at diagnosis, to have never taken any glucose-lowering medication, to have lost weight since diabetes diagnosis, and to have had bariatric surgery.
https://diabetes.acponline.org/archives/2021/11/12/1.htm
12 Nov 2021
Consensus report issued on management of type 1 diabetes in adults
The report from the American Diabetes Association and European Association for the Study of Diabetes offers guidance on diagnosis, management, and treatment, among other topics. Their recommendations are evidence-based where possible but represent the consensus opinion of the authors.
https://diabetes.acponline.org/archives/2021/10/08/1.htm
8 Oct 2021
Hospitalizations for diabetes complications fell, were replaced by other causes
An analysis of excess hospitalizations among people with diabetes in England from 2003 to 2018 found that diabetes caused fewer of their hospital stays, with respiratory disease and cancer becoming more predominant diagnoses.
https://diabetes.acponline.org/archives/2021/12/10/1.htm
10 Dec 2021