Search results for "Highlights"

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SGLT-2 inhibitors associated with increased risk for diabetic ketoacidosis

A cohort study found a threefold increase in the risk for diabetic ketoacidosis with sodium-glucose cotransporter-2 (SGLT-2) inhibitors compared to dipeptidyl peptidase-4 (DPP-4) inhibitors, with possible variation by severity or duration of diabetes.
14 Aug 2020

Association between diabetes and worse COVID-19 outcomes more marked in younger adults

Among patients hospitalized with COVID-19, diabetes was a more significant risk factor for death, intensive care, or intubation in those younger than 50 years compared to older patients, a retrospective French study found.
11 Jun 2021

Depression associated with death in older patients with type 2 diabetes

A study that screened patients with type 2 diabetes in Spain for depression found that depression was associated with higher all-cause mortality in patients older than age 65 years, but not in younger patients.
11 Jun 2021

Younger age at type 2 diabetes onset linked to higher risk of subsequent dementia

An analysis of a prospective cohort study in the U.K. found that developing type 2 diabetes before age 70 years was associated with greater likelihood of having dementia, and dementia risk increased with longer duration of diabetes.
14 May 2021

More guideline-recommended diabetes care provided to older U.S. adults, not other age groups

From 2005 to 2018, the proportion of diabetes patients receiving care as recommended by the American Diabetes Association increased from 29.3% to 44.2% among those ages 65 years or older but did not change significantly for those ages 40 to 64 years (25.2% to 25.8%) or 20 to 39 years (9.9% to 26.0%).
14 May 2021

CGM improves glucose control in high-risk groups with type 1 diabetes, studies find

Continuous glucose monitoring (CGM) was associated with improved HbA1c levels among adolescents and young adults in one trial and less hypoglycemia among older adults in another.
10 Jul 2020

AHA issues policy statement on reducing lower-extremity amputations

Amputations among U.S. patients with diabetes decreased between 2000 and 2009 but increased by 50% from 2009 to 2015, leading the American Heart Association (AHA) to call for better identification and treatment of peripheral artery disease and propose policy solutions.
9 Apr 2021

GLP-1 receptor agonists, thiazolidinediones associated with lower risk of ischemic stroke

A recent meta-analysis from Denmark looked at patients with genetic variations that cause increases in plasma glucose levels and found that their elevated ischemic stroke risk appeared to be mitigated by treatment with certain classes of diabetes drugs.
9 Apr 2021

Exercise and CBT are cost-effective for diabetes patients with depression

A study used simulation modeling to project the long-term effects of a three-month exercise and cognitive behavioral therapy (CBT) intervention for patients with type 2 diabetes and major depressive disorder. It found clear cost-effectiveness with the interventions alone or combined.
12 Mar 2021

KDIGO made 12 recommendations for managing diabetes with CKD

The kidney group's guideline supports metformin and sodium–glucose cotransporter-2 inhibitors as first-line therapies for patients with chronic kidney disease (CKD) based on consistent trial data showing their effectiveness, noted an ACP Journal Club commentary.
12 Mar 2021

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