Search results for "Highlights"
Moderating carbohydrates associated with lower mortality rates in type 2 diabetes
An observational study based on U.S. data compared hazard ratios for death based on overall, unhealthy, and healthy low-carb diet scores according to percentage of energy obtained from total and subtypes of carbohydrate, protein, and fat.
https://diabetes.acponline.org/archives/2022/05/13/1.htm
13 May 2022
KDIGO made 12 recommendations for managing diabetes with CKD
The kidney group's guideline supports metformin and sodium–glucose cotransporter-2 inhibitors as first-line therapies for patients with chronic kidney disease (CKD) based on consistent trial data showing their effectiveness, noted an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2021/03/12/6.htm
12 Mar 2021
GLP-1 receptor agonists, thiazolidinediones associated with lower risk of ischemic stroke
A recent meta-analysis from Denmark looked at patients with genetic variations that cause increases in plasma glucose levels and found that their elevated ischemic stroke risk appeared to be mitigated by treatment with certain classes of diabetes drugs.
https://diabetes.acponline.org/archives/2021/04/09/2.htm
9 Apr 2021
Program directs stable diabetes patients from endocrinology back to primary care
One academic health system developed a program to “graduate” patients out of endocrinology visits for their diabetes. Criteria included HbA1c level less than 8.0%, blood pressure less than 140/90 mm Hg, no tobacco use, and use of statins and aspirin if needed.
https://diabetes.acponline.org/archives/2022/09/16/1.htm
16 Sep 2022
Exercise and CBT are cost-effective for diabetes patients with depression
A study used simulation modeling to project the long-term effects of a three-month exercise and cognitive behavioral therapy (CBT) intervention for patients with type 2 diabetes and major depressive disorder. It found clear cost-effectiveness with the interventions alone or combined.
https://diabetes.acponline.org/archives/2021/03/12/3.htm
12 Mar 2021
More guideline-recommended diabetes care provided to older U.S. adults, not other age groups
From 2005 to 2018, the proportion of diabetes patients receiving care as recommended by the American Diabetes Association increased from 29.3% to 44.2% among those ages 65 years or older but did not change significantly for those ages 40 to 64 years (25.2% to 25.8%) or 20 to 39 years (9.9% to 26.0%).
https://diabetes.acponline.org/archives/2021/05/14/2.htm
14 May 2021
SGLT-2 inhibitors linked to more diabetic ketoacidosis vs. DPP-4 inhibitors or sulfonylureas
A retrospective study found that new users of sodium-glucose cotransporter-2 (SGLT-2) inhibitors developed diabetic ketoacidosis at a rate of about 6 per 1,000 person-years, compared to 4.3 or 4.5 per 1,000 person-years with dipeptidyl peptidase-4 (DPP-4) inhibitors or sulfonylureas, respectively.
https://diabetes.acponline.org/archives/2022/03/11/1.htm
11 Mar 2022
Tirzepatide may improve glycemic control when added to insulin glargine in type 2 diabetes
An industry-sponsored phase 3 trial found statistically significant improvements in HbA1c level among patients with type 2 diabetes who had inadequate glycemic control on insulin glargine and were randomly assigned to subcutaneous tirzepatide once weekly versus placebo.
https://diabetes.acponline.org/archives/2022/02/11/1.htm
11 Feb 2022
Studies find link between metformin and reduced COVID-19 mortality, mixed results for DPP-4 inhibitors
Prior metformin use was associated with a threefold decrease in mortality from COVID-19 in one study of patients with type 2 diabetes, while three other studies found mixed results on whether dipeptidyl peptidase-4 (DPP-4) inhibitors affect COVID-19 outcomes.
https://diabetes.acponline.org/archives/2021/02/12/2.htm
12 Feb 2021
Nearly 5% of adults diagnosed with type 2 diabetes in Scotland were in remission in 2019
Compared with people who did not achieve remission, those in remission tended to be older, to have a lower HbA1c level at diagnosis, to have never taken any glucose-lowering medication, to have lost weight since diabetes diagnosis, and to have had bariatric surgery.
https://diabetes.acponline.org/archives/2021/11/12/1.htm
12 Nov 2021