Search results for "Highlights"
Patients with type 2 diabetes and all risk factors controlled still have increased CVD risk
Risk factor control was more strongly associated with mortality risk among patients with cardiorenal disease than those without, according to a retrospective British study.
https://diabetes.acponline.org/archives/2020/12/11/3.htm
11 Dec 2020
Balanced crystalloids may be preferred for acute resolution of diabetic ketoacidosis
A small subgroup analysis of two randomized trials found that median time to resolution of diabetic ketoacidosis was 13 hours in patients who received balanced crystalloids versus nearly 17 hours in those who received saline.
https://diabetes.acponline.org/archives/2020/12/11/2.htm
11 Dec 2020
SGLT-2 inhibitors linked to more diabetic ketoacidosis vs. DPP-4 inhibitors or sulfonylureas
A retrospective study found that new users of sodium-glucose cotransporter-2 (SGLT-2) inhibitors developed diabetic ketoacidosis at a rate of about 6 per 1,000 person-years, compared to 4.3 or 4.5 per 1,000 person-years with dipeptidyl peptidase-4 (DPP-4) inhibitors or sulfonylureas, respectively.
https://diabetes.acponline.org/archives/2022/03/11/1.htm
11 Mar 2022
Studies find link between metformin and reduced COVID-19 mortality, mixed results for DPP-4 inhibitors
Prior metformin use was associated with a threefold decrease in mortality from COVID-19 in one study of patients with type 2 diabetes, while three other studies found mixed results on whether dipeptidyl peptidase-4 (DPP-4) inhibitors affect COVID-19 outcomes.
https://diabetes.acponline.org/archives/2021/02/12/2.htm
12 Feb 2021
In type 2 diabetes patients, lower LDL cholesterol levels after PCI associated with better outcomes
A pooled analysis of three randomized clinical trials found reductions in major adverse cardiac or cerebrovascular events after percutaneous coronary intervention (PCI) at 3.9-year follow-up only in patients with low-density lipoprotein (LDL) cholesterol levels below 70 mg/dL at one year.
https://diabetes.acponline.org/archives/2020/11/13/3.htm
13 Nov 2020
Tirzepatide may improve glycemic control when added to insulin glargine in type 2 diabetes
An industry-sponsored phase 3 trial found statistically significant improvements in HbA1c level among patients with type 2 diabetes who had inadequate glycemic control on insulin glargine and were randomly assigned to subcutaneous tirzepatide once weekly versus placebo.
https://diabetes.acponline.org/archives/2022/02/11/1.htm
11 Feb 2022
One-time serum C-peptide testing detected patients misclassified as having type 1 diabetes
In a recent study, a serum C-peptide testing program resulted in reclassification of the cause of diabetes in about 7% of the cohort tested at one diabetes center in Scotland. Reclassification was most likely in those diagnosed at age 30 years or older.
https://diabetes.acponline.org/archives/2020/11/13/2.htm
13 Nov 2020
Surgical, drug treatments have similar outcomes in patients with vitreous hemorrhage from proliferative diabetic retinopathy
A randomized trial found equivalent improvements in visual acuity at two years with either therapy but identified some differences in outcomes that could help patients and clinicians choose a treatment method.
https://diabetes.acponline.org/archives/2021/01/08/2.htm
8 Jan 2021
Neurologists update guideline on treatment of painful diabetic neuropathy
The updated guideline from the American Academy of Neurology supports offering tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitors, gabapentinoids, and/or sodium channel blockers to reduce pain from diabetic neuropathy.
https://diabetes.acponline.org/archives/2022/01/14/1.htm
14 Jan 2022
Nearly 5% of adults diagnosed with type 2 diabetes in Scotland were in remission in 2019
Compared with people who did not achieve remission, those in remission tended to be older, to have a lower HbA1c level at diagnosis, to have never taken any glucose-lowering medication, to have lost weight since diabetes diagnosis, and to have had bariatric surgery.
https://diabetes.acponline.org/archives/2021/11/12/1.htm
12 Nov 2021