Search results for "Highlights"
Study finds long-term reductions in cardiovascular risk factors with SGLT-2 inhibitors
While the meta-analysis also found durable reductions in macrovascular complications and mortality with sodium-glucose cotransporter-2 (SGLT-2) inhibitors versus placebo, there were insufficient data comparing the drug class to other antihyperglycemic medications.
https://diabetes.acponline.org/archives/2021/12/10/2.htm
10 Dec 2021
Newer oral diabetes meds could provide significant benefits in type 1 diabetes
A retrospective chart review found that glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors were associated with benefits including weight loss and reduced use of insulin in patients with type 1 diabetes.
https://diabetes.acponline.org/archives/2022/11/11/1.htm
11 Nov 2022
Antidepressant adherence linked to lower risk of advanced complications of diabetes
In patients with diabetes and depression in Taiwan, regular use of an antidepressant was associated with a 0.92-fold decreased risk of macrovascular complications and a 0.86-fold decreased risk of all-cause mortality compared with poor adherence.
https://diabetes.acponline.org/archives/2021/08/13/2.htm
13 Aug 2021
GLP-1 receptor agonists improved cardiovascular, kidney outcomes in type 2 diabetes
In a systematic review and meta-analysis of eight randomized controlled trials, glucagon-like peptide-1 (GLP-1) receptor agonists reduced major adverse cardiovascular events by 14%, all-cause mortality by 12%, hospital admission for heart failure by 11%, and a composite kidney outcome by 21%, with no increase in safety outcomes.
https://diabetes.acponline.org/archives/2021/09/10/3.htm
10 Sep 2021
Association between diabetes and worse COVID-19 outcomes more marked in younger adults
Among patients hospitalized with COVID-19, diabetes was a more significant risk factor for death, intensive care, or intubation in those younger than 50 years compared to older patients, a retrospective French study found.
https://diabetes.acponline.org/archives/2021/06/11/3.htm
11 Jun 2021
Diets with low glycemic index or glycemic load may benefit patients with diabetes
A systematic review and meta-analysis found small improvements in established targets for glycemic control, blood lipids, adiposity, and inflammation among those with moderately controlled type 1 and type 2 disease who tried low glycemic index/load diets.
https://diabetes.acponline.org/archives/2021/08/13/3.htm
13 Aug 2021
Younger age at type 2 diabetes onset linked to higher risk of subsequent dementia
An analysis of a prospective cohort study in the U.K. found that developing type 2 diabetes before age 70 years was associated with greater likelihood of having dementia, and dementia risk increased with longer duration of diabetes.
https://diabetes.acponline.org/archives/2021/05/14/3.htm
14 May 2021
SGLT-2 inhibitors associated with increased risk for diabetic ketoacidosis
A cohort study found a threefold increase in the risk for diabetic ketoacidosis with sodium-glucose cotransporter-2 (SGLT-2) inhibitors compared to dipeptidyl peptidase-4 (DPP-4) inhibitors, with possible variation by severity or duration of diabetes.
https://diabetes.acponline.org/archives/2020/08/14/2.htm
14 Aug 2020
DPP-4 inhibitors associated with risk of cholecystitis, meta-analysis finds
Patients with type 2 diabetes who were randomized to receive dipeptidyl peptidase-4 (DPP-4) inhibitors had higher rates of gallbladder disease than those who got placebo or nonincretin drugs, but no difference in risk of cholelithiasis or biliary diseases.
https://diabetes.acponline.org/archives/2022/07/08/1.htm
8 Jul 2022
PPIs may have beneficial glycemic effects in patients with diabetes
A systematic review and meta-analysis found that proton-pump inhibitors (PPIs) improved glycemic indices in patients with diabetes and did not appear to affect risk for incident diabetes.
https://diabetes.acponline.org/archives/2021/07/09/2.htm
9 Jul 2021