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Spotlight on cognitive effects of diabetes

Two recent studies looked at the effects of diabetes on the brain, one focusing on mild cognitive impairment and the other on brain imaging findings.
https://diabetes.acponline.org/archives/2017/05/12/5.htm
12 May 2017

Screening tool identifies high-risk drivers with type 1 diabetes and website helps to avoid future accidents

Significant independent predictors of risk for driving mishaps included annual driving distance and presence of peripheral neuropathy. Researchers developed an 11-item questionnaire to further refine risk prediction.
https://diabetes.acponline.org/archives/2017/05/12/3.htm
12 May 2017

Treatment deintensification uncommon in type 2 diabetes

Less than a quarter of patients with an HbA1c below 6.0% had a drug discontinued or a dosage decreased, even after the American Diabetes Association issued a practice advisory about the risk of mortality associated with intensive glucose control.
https://diabetes.acponline.org/archives/2017/05/12/2.htm
12 May 2017

Macular edema, cardiovascular disease associated in type 2 diabetes

Patients with diabetic macular edema or proliferative diabetic retinopathy should be followed more actively to prevent cardiovascular disease, study authors said.
https://diabetes.acponline.org/archives/2017/05/12/1.htm
12 May 2017

SGLT2 inhibitors may have class effect for reduction of cardiac risk

The industry-funded study used international data to compare rates of heart failure hospitalization and mortality in patients on sodium glucose cotransporter-2 (SGLT2) inhibitors or other glucose-lowering drugs.
https://diabetes.acponline.org/archives/2017/06/09/3.htm
9 Jun 2017

Oral glucose tolerance test results may be influenced by height, study finds

Among both men and women in Finland, height was inversely associated with two-hour plasma glucose concentration, except among patients with a body-mass index of 35 kg/m2 or more.
https://diabetes.acponline.org/archives/2017/06/09/2.htm
9 Jun 2017

Basal-bolus insulin may require fewer increases in daily doses than other insulin regimens

An observational trial compared insulin glargine once daily, biphasic insulin twice daily, and biphasic insulin three times daily with a basal-bolus regimen of rapid-acting insulin analogue three times daily and long-acting insulin once daily.
https://diabetes.acponline.org/archives/2017/06/09/1.htm
9 Jun 2017

No increase in mortality with incretin-based drugs compared to other diabetes meds, review finds

The review included 189 randomized controlled trials that compared glucagon-like peptide-1 receptor agonists or dipeptidyl peptidase-2 inhibitors with placebo or other diabetes drugs in patients with type 2 diabetes.
https://diabetes.acponline.org/archives/2017/07/14/3.htm
14 Jul 2017

Glucose self-monitoring had no effect on glycemic control in non–insulin-treated type 2 diabetes

Although it would seem to make sense that routine glucose self-monitoring provides better outcomes, this long-held belief is not supported by the data, said an editor's note accompanying the study.
https://diabetes.acponline.org/archives/2017/07/14/1.htm
14 Jul 2017

Canagliflozin may have lower risk of cardiovascular events compared to placebo, industry-funded study finds

The study found a higher risk of amputation of toes, feet, or legs with canagliflozin than with placebo, with most amputations occurring at the toe or metatarsal.
https://diabetes.acponline.org/archives/2017/07/14/2.htm
14 Jul 2017

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