Search results for "From ACP Journal Club"


 
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Canagliflozin reduced kidney failure and CV events at 2.6 years in type 2 diabetes with chronic kidney disease

Sodium–glucose cotransporter 2 inhibitors appear to be a promising treatment option for patients with diabetes and chronic kidney disease, according to an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2019/09/13/6.htm
13 Sep 2019

In uncontrolled type 2 diabetes, adjunctive semaglutide reduced HbA1c and body weight vs sitagliptin

The trial showed that an oral glucagon-like peptide-1–receptor analogue improved glycemic control compared to a dipeptidyl peptidase 4 inhibitor, but gastrointestinal side effects and cost remain barriers to use of the former class.
https://diabetes.acponline.org/archives/2019/09/13/7.htm
13 Sep 2019

Studies show benefits of glucagon-like peptide-1 receptor agonists

A commentary reviewed the findings of REWIND, PIONEER 6, and PIONEER 4 trials, which studied the cardiovascular and glycemic control effects of dulaglutide, semaglutide, and liraglutide.
https://diabetes.acponline.org/archives/2019/10/11/7.htm
11 Oct 2019

Continuous glucose monitoring reduced hypoglycemia over 6 months

The positive results of a trial of continuous glucose monitoring in type 1 diabetes patients ages 60 years and older support recommending the technology to this group, according to an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2020/12/11/10.htm
11 Dec 2020

Review: Viscous fiber reduces HbA1c, fasting glucose, and insulin resistance in type 2 diabetes

An ACP Journal Club commentary recommends advising patients with type 2 diabetes who don't smoke and who take metformin to also consider increasing their soluble fiber intake by more than 10 g/d.
https://diabetes.acponline.org/archives/2019/06/14/6.htm
14 Jun 2019

In type 2 diabetes with periodontitis, intensive periodontitis treatment improved glycemic control at 1 year

Putting these findings into practice may require incorporating dental professionals into diabetes care teams and training clinicians who treat patients with diabetes to recognize and assess periodontal disease and make appropriate referrals, the ACP Journal Club commentary said.
https://diabetes.acponline.org/archives/2019/05/10/8.htm
10 May 2019

Review: Rapid-acting analogues do not differ from regular human insulin for mortality or HbA1c in type 2 diabetes

The review shows that, contrary to specialty recommendations, there is no reason not to use regular human insulins, which are less costly than analogue insulins, said an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2019/05/10/7.htm
10 May 2019

Studies analyze amputation rates with sodium–glucose cotransporter-2 inhibitors

An ACP Journal Club commentary looked at studies on the effects of canagliflozin in patients with cardiovascular disease and dapagliflozin in patients with peripheral artery disease, concluding that amputation risks are small enough that they needn't play a major role in prescribing decisions.
https://diabetes.acponline.org/archives/2021/02/12/7.htm
12 Feb 2021

In stable CAD with type 2 diabetes, adding ticagrelor to aspirin reduced CV events but increased major bleeding

Although an industry-funded trial found little net benefit overall from adding ticagrelor to aspirin, it's possible that some patients with higher ischemic risk and low bleeding risk could benefit, according to an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2020/02/14/6.htm
14 Feb 2020

In diabetes with no CVD, aspirin reduced serious vascular events but increased major bleeding at 7.4 years

The results of a recent trial of aspirin for cardiovascular disease (CVD) prevention in diabetes challenge current guidelines and the opinion of many clinicians of the net benefit of the drug, according to an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2019/01/11/6.htm
11 Jan 2019

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