Review: Sulfonylureas are associated with overall mortality and CV events vs other antihyperglycemics | ACP Diabetes Monthly
A review looked at randomized trials that compared mortality rates among patients taking sulfonylureas versus several other classes of hypoglycemic drugs.
Review: Metformin is linked to reduced mortality in type 2 diabetes with comorbid CKD and CHF | ACP Diabetes Monthly
The included studies focused on metformin use in patients with chronic kidney disease (CKD), congestive heart failure (CHF), chronic liver disease (CLD), or older age.
In type 1 diabetes, adding liraglutide to insulin increased hypoglycemia and hyperglycemia with ketosis | ACP Diabetes Monthly
The study authors concluded that the negative effects observed would limit clinical use of liraglutide in patients with type 1 diabetes.
Gastric bypass or biliopancreatic diversion increases remission from type 2 diabetes in obese adults | ACP Diabetes Monthly
A randomized controlled trial (RCT) of 60 severely obese adults with type 2 diabetes found that gastric bypass or biliopancreatic diversion increased diabetes remission more than medical therapy.
In patients with type 2 diabetes and high CV risk, liraglutide reduced a composite CV outcome at a median 3.8 y | ACP Diabetes Monthly
The study's primary composite outcome was first occurrence of death from cardiovascular (CV) causes, nonfatal (including silent) myocardial infarction, or nonfatal stroke.
In uncontrolled type 2 diabetes, CBT improved glycemic control and reduced depression | ACP Diabetes Monthly
Patients with diabetes and depression who received cognitive behavioral therapy (CBT) had improvements in medication adherence, self-monitoring of glucose, depressive symptoms, and HbA1c compared to those who received usual care.
While exenatide can be considered a second-line option for patients with type 2 diabetes and some may prefer its once-weekly dosing, those at high cardiovascular risk should receive agents with demonstrated cardiovascular benefit, according to an
Review: Bariatric surgery improves weight and glycemia in nonmorbidly obese adults with diabetes | ACP Diabetes Monthly
A review of 3 randomized controlled trials found that surgical treatment increased weight loss and improved diabetes-related outcomes more than nonsurgical treatment in moderately obese patients.
ACP Diabetes Monthly delivers a monthly summary of news about diabetes, including the latest research, clinical guidelines, and FDA drug actions.
Self-monitoring of blood glucose did not improve HbA1c or QOL at 1 year in non-insulin-treated type 2 diabetes | ACP Diabetes Monthly
The randomized controlled trial adds to the evidence about routine use of self-monitoring of blood glucose for all patients with type 2 diabetes, according to an ACP Journal Club commentary.