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Combined canagliflozin, metformin may offer better glycemic control than monotherapy, study finds

The industry-funded, double-blind, randomized, controlled trial assigned adult patients with type 2 diabetes who were not taking antihyperglycemic agents before the study to 26 weeks of treatment in 1 of 5 arms.
https://diabetes.acponline.org/archives/2016/02/12/2.htm
12 Feb 2016

Diabetes, prior CHD may not be equivalent CHD risk factors, study indicates

The population-based prospective cohort analysis of adults who were members of a single U.S. health care delivery system compared CHD risk among those with and without a history of diabetes or CHD.
https://diabetes.acponline.org/archives/2016/01/08/2.htm
8 Jan 2016

Continuous glucose monitoring may help type 2 diabetes patients

An industry-funded trial found slight decreases in HbA1c among insulin-using patients with type 2 diabetes who tried continuous glucose monitoring, compared to usual care.
https://diabetes.acponline.org/archives/2017/09/08/1.htm
8 Sep 2017

New risk score for CVD may be easier to use than existing scores in patients with diabetes

Researchers used data from the ADVANCE-ON study to develop the AD-ON risk score, a 10-year risk score for the combined endpoint of major cardiovascular disease (CVD) or chronic kidney disease.
https://diabetes.acponline.org/archives/2016/02/12/3.htm
12 Feb 2016

FDA warns about ketoacidosis and urinary tract infections with SGLT2 inhibitors

The warnings are based on a review finding 73 cases of ketoacidosis in patients with type 1 or type 2 diabetes and 19 cases of life-threatening urosepsis and pyelonephritis.
https://diabetes.acponline.org/archives/2015/12/11/2.htm
11 Dec 2015

Collaboration between generalists, subspecialists can improve glycemic control

A “virtual clinic” model involving consultations between diabetes subspecialists and primary care physicians was associated with glycemic improvements in treated patients and controls from the same practices, a British study found.
https://diabetes.acponline.org/archives/2015/12/11/3.htm
11 Dec 2015

Glucose-lowering agents other than metformin associated with higher mortality in study

Compared to matched controls, patients on metformin monotherapy did not show significant excess mortality during follow-up, but patients on sulfonylurea or insulin monotherapy had higher mortality rates.
https://diabetes.acponline.org/archives/2016/01/08/3.htm
8 Jan 2016

Basal-bolus insulin may require fewer increases in daily doses than other insulin regimens

An observational trial compared insulin glargine once daily, biphasic insulin twice daily, and biphasic insulin three times daily with a basal-bolus regimen of rapid-acting insulin analogue three times daily and long-acting insulin once daily.
https://diabetes.acponline.org/archives/2017/06/09/1.htm
9 Jun 2017

DPP-4 inhibitors associated with lower mortality and cardiac risk than sulfonylureas as add-on therapy, study finds

When added to metformin, DPP-4 inhibitors were associated with reduced risks for all-cause death and stroke but did not appear to alter the risks for myocardial infarction and hospitalization for heart failure relative to sulfonylureas.
https://diabetes.acponline.org/archives/2015/11/13/3.htm
13 Nov 2015

Patients with prediabetes diagnosis more likely to change health behaviors

Patients who are aware of their prediabetes are more likely to adopt lifestyle changes that reduce the risk of developing diabetes, according to a recent study.
https://diabetes.acponline.org/archives/2015/07/10/2.htm
10 Jul 2015

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