Search results for "Highlights"
GLP-1 receptor agonists, thiazolidinediones associated with lower risk of ischemic stroke
A recent meta-analysis from Denmark looked at patients with genetic variations that cause increases in plasma glucose levels and found that their elevated ischemic stroke risk appeared to be mitigated by treatment with certain classes of diabetes drugs.
https://diabetes.acponline.org/archives/2021/04/09/2.htm
9 Apr 2021
Task Force draft recommendation supports earlier diabetes screening
The draft recommendation calls for screening patients ages 35 to 70 years who are overweight or obese. It is open for public comment through Monday, April 12.
https://diabetes.acponline.org/archives/2021/04/09/1.htm
9 Apr 2021
No differences seen in outcomes with one-step vs. two-step gestational diabetes screening
The one-step screening process, which used a two-hour fasting glucose tolerance test, found more cases of gestational diabetes in a randomized trial, but perinatal and maternal complications did not differ.
https://diabetes.acponline.org/archives/2021/03/12/2.htm
12 Mar 2021
KDIGO made 12 recommendations for managing diabetes with CKD
The kidney group's guideline supports metformin and sodium–glucose cotransporter-2 inhibitors as first-line therapies for patients with chronic kidney disease (CKD) based on consistent trial data showing their effectiveness, noted an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2021/03/12/6.htm
12 Mar 2021
Exercise and CBT are cost-effective for diabetes patients with depression
A study used simulation modeling to project the long-term effects of a three-month exercise and cognitive behavioral therapy (CBT) intervention for patients with type 2 diabetes and major depressive disorder. It found clear cost-effectiveness with the interventions alone or combined.
https://diabetes.acponline.org/archives/2021/03/12/3.htm
12 Mar 2021
Incidence of diagnosed diabetes may be stable or declining in many countries
An analysis of 21 mostly high-income countries or jurisdictions found a downward or stable trend in clinically diagnosed diabetes incidence in recent years, but the drivers of these trends remain unknown, an accompanying editorial comment said.
https://diabetes.acponline.org/archives/2021/03/12/1.htm
12 Mar 2021
Choice of SGLT-2 inhibitors, GLP-1 receptor agonists should be based on individual risk
A meta-analysis comparing sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists found differing effects, including that the SGLT-2 inhibitors affected heart failure outcomes while GLP-1 receptor agonists reduced stroke risk.
https://diabetes.acponline.org/archives/2021/02/12/3.htm
12 Feb 2021
Studies find link between metformin and reduced COVID-19 mortality, mixed results for DPP-4 inhibitors
Prior metformin use was associated with a threefold decrease in mortality from COVID-19 in one study of patients with type 2 diabetes, while three other studies found mixed results on whether dipeptidyl peptidase-4 (DPP-4) inhibitors affect COVID-19 outcomes.
https://diabetes.acponline.org/archives/2021/02/12/2.htm
12 Feb 2021
Most cases of prediabetes in older adults did not progress to diabetes, study finds
A cohort study of older adults found a high prevalence of prediabetes, but during more than six years of follow-up, death or regression to normoglycemia was more common than progression to diabetes.
https://diabetes.acponline.org/archives/2021/02/12/1.htm
12 Feb 2021
Biomarker score predicts heart failure risk with diabetes and prediabetes
The score, which was based on cardiac troponin, N-terminal pro-B-type natriuretic peptide, C-reactive protein, and electrocardiography, could be used to target specific therapies to the highest-risk patients, study authors said.
https://diabetes.acponline.org/archives/2021/01/08/3.htm
8 Jan 2021