Search results for "From ACP Journal Club"
A lifestyle intervention did not reduce cardiovascular outcomes in overweight or obese patients with type 2 diabetes
The Look AHEAD trial randomized more than 5,000 overweight and obese type 2 diabetics to intensive lifestyle intervention or diabetes support and education and found that the intensive group reduced several risk factors, but not the primary outcome.
https://diabetes.acponline.org/archives/2013/11/08/8.htm
8 Nov 2013
Review: Intensive blood pressure control reduces stroke, but not mortality or MI, in type 2 diabetes
A meta-analysis compared five studies (including the ACCORD trial) that treated adults with type 2 diabetes with antihypertensive therapies to achieve prespecified blood pressure targets.
https://diabetes.acponline.org/archives/2013/02/08/8.htm
8 Feb 2013
Mediterranean diets reduced cardiovascular events more than a low-fat diet in high-risk persons
A randomized controlled trial (RCT) in Spain included older patients with type 2 diabetes mellitus or at least three major risk factors for cardiovascular disease.
https://diabetes.acponline.org/archives/2013/07/12/7.htm
12 Jul 2013
Safety of dipeptidyl peptidase-4 inhibitors analyzed in 2 studies
A meta-analysis of dipeptidyl peptidase-4 inhibitors showed no increase in pancreatic adverse events, while a trial of saxagliptin found no effect on the overall rate of cardiovascular events.
https://diabetes.acponline.org/archives/2014/02/14/7.htm
14 Feb 2014
Neither n-3 fatty acid supplements nor glargine reduced CV events in patients with dysglycemia
The Outcome Reduction with an Initial Glargine Intervention trial randomized about 12,000 patients with cardiovascular risk factors and dysglycemia to basal insulin glargine or usual care and daily n-3 fatty acid supplementation or olive oil placebo.
https://diabetes.acponline.org/archives/2012/10/12/8.htm
12 Oct 2012