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Individualizing glycemic control could reduce costs, increase quality-adjusted life-years

A cost-effectiveness analysis found that individualized control saved $13,547 per patient compared with uniform intensive control, primarily due to lower medication costs, and increased quality-adjusted life-years by 0.10.
https://diabetes.acponline.org/archives/2018/01/12/3.htm
12 Jan 2018

Tool may help stratify risk for hypoglycemia-related ED and hospital use

The hypoglycemia risk stratification tool is based on six variables: previous episodes of hypoglycemia-related hospital utilization, insulin use, sulfonylurea use, ED use in the previous year, chronic kidney disease stage, and age.
https://diabetes.acponline.org/archives/2017/09/08/3.htm
8 Sep 2017

Impaired glucose tolerance at 1 hour may be more predictive than at 2 hours, study finds

The results highlight the potential benefit of targeting individuals with an elevated one-hour blood glucose level and, if supported by additional evidence, eventually replacing the two-hour test with a one-hour measure, the authors said.
https://diabetes.acponline.org/archives/2017/12/08/2.htm
8 Dec 2017

Switching to sulfonylureas from metformin monotherapy may increase risk of cardiovascular, hypoglycemic events

The results suggest that continuing metformin alone and accepting higher HbA1c targets may be preferable to switching to sulfonylureas when considering macrovascular outcomes and hypoglycemia, an accompanying editorial said.
https://diabetes.acponline.org/archives/2018/08/10/1.htm
10 Aug 2018

Canagliflozin may have lower risk of cardiovascular events compared to placebo, industry-funded study finds

The study found a higher risk of amputation of toes, feet, or legs with canagliflozin than with placebo, with most amputations occurring at the toe or metatarsal.
https://diabetes.acponline.org/archives/2017/07/14/2.htm
14 Jul 2017

Insulin pump didn't improve glycemic control compared to training on injections

British patients with type 1 diabetes were enrolled in group training courses that taught flexible intensive insulin treatment and then randomized to an insulin pump or multiple daily injections and followed for two years.
https://diabetes.acponline.org/archives/2017/04/14/3.htm
14 Apr 2017

One-hour glucose tolerance test outperforms two-hour test for predicting progression to diabetes

Machine learning was used to combine different variables, including clinical risk factors, plasma glucose and insulin levels, HbA1c level, and six metabolic markers, in 1,527 models for predicting progression risk.
https://diabetes.acponline.org/archives/2018/12/14/1.htm
14 Dec 2018

Weekly GLP-1 analogue associated with reduced MI, stroke risk, industry study finds

The trial of semaglutide included 3,297 patients with type 2 diabetes, 83% of whom had established cardiovascular disease, chronic kidney disease, or both.
https://diabetes.acponline.org/archives/2016/10/07/3.htm
7 Oct 2016

New consensus statement on type 2 diabetes changes recommended drugs

The recommendations from the American Diabetes Association and the European Association for the Study of Diabetes encourage use of sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists.
https://diabetes.acponline.org/archives/2018/10/12/1.htm
12 Oct 2018

Spotlight on cognitive effects of diabetes

Two recent studies looked at the effects of diabetes on the brain, one focusing on mild cognitive impairment and the other on brain imaging findings.
https://diabetes.acponline.org/archives/2017/05/12/5.htm
12 May 2017

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