Search results for "Highlights"
PPIs may have beneficial glycemic effects in patients with diabetes
A systematic review and meta-analysis found that proton-pump inhibitors (PPIs) improved glycemic indices in patients with diabetes and did not appear to affect risk for incident diabetes.
https://diabetes.acponline.org/archives/2021/07/09/2.htm
9 Jul 2021
SGLT-2 inhibitors associated with increased risk for diabetic ketoacidosis
A cohort study found a threefold increase in the risk for diabetic ketoacidosis with sodium-glucose cotransporter-2 (SGLT-2) inhibitors compared to dipeptidyl peptidase-4 (DPP-4) inhibitors, with possible variation by severity or duration of diabetes.
https://diabetes.acponline.org/archives/2020/08/14/2.htm
14 Aug 2020
Younger age at type 2 diabetes onset linked to higher risk of subsequent dementia
An analysis of a prospective cohort study in the U.K. found that developing type 2 diabetes before age 70 years was associated with greater likelihood of having dementia, and dementia risk increased with longer duration of diabetes.
https://diabetes.acponline.org/archives/2021/05/14/3.htm
14 May 2021
DPP-4 inhibitors associated with risk of cholecystitis, meta-analysis finds
Patients with type 2 diabetes who were randomized to receive dipeptidyl peptidase-4 (DPP-4) inhibitors had higher rates of gallbladder disease than those who got placebo or nonincretin drugs, but no difference in risk of cholelithiasis or biliary diseases.
https://diabetes.acponline.org/archives/2022/07/08/1.htm
8 Jul 2022
Program directs stable diabetes patients from endocrinology back to primary care
One academic health system developed a program to “graduate” patients out of endocrinology visits for their diabetes. Criteria included HbA1c level less than 8.0%, blood pressure less than 140/90 mm Hg, no tobacco use, and use of statins and aspirin if needed.
https://diabetes.acponline.org/archives/2022/09/16/1.htm
16 Sep 2022
KDIGO made 12 recommendations for managing diabetes with CKD
The kidney group's guideline supports metformin and sodium–glucose cotransporter-2 inhibitors as first-line therapies for patients with chronic kidney disease (CKD) based on consistent trial data showing their effectiveness, noted an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2021/03/12/6.htm
12 Mar 2021
CGM improves glucose control in high-risk groups with type 1 diabetes, studies find
Continuous glucose monitoring (CGM) was associated with improved HbA1c levels among adolescents and young adults in one trial and less hypoglycemia among older adults in another.
https://diabetes.acponline.org/archives/2020/07/10/2.htm
10 Jul 2020
AHA issues policy statement on reducing lower-extremity amputations
Amputations among U.S. patients with diabetes decreased between 2000 and 2009 but increased by 50% from 2009 to 2015, leading the American Heart Association (AHA) to call for better identification and treatment of peripheral artery disease and propose policy solutions.
https://diabetes.acponline.org/archives/2021/04/09/3.htm
9 Apr 2021
Exercise and CBT are cost-effective for diabetes patients with depression
A study used simulation modeling to project the long-term effects of a three-month exercise and cognitive behavioral therapy (CBT) intervention for patients with type 2 diabetes and major depressive disorder. It found clear cost-effectiveness with the interventions alone or combined.
https://diabetes.acponline.org/archives/2021/03/12/3.htm
12 Mar 2021
GLP-1 receptor agonists, thiazolidinediones associated with lower risk of ischemic stroke
A recent meta-analysis from Denmark looked at patients with genetic variations that cause increases in plasma glucose levels and found that their elevated ischemic stroke risk appeared to be mitigated by treatment with certain classes of diabetes drugs.
https://diabetes.acponline.org/archives/2021/04/09/2.htm
9 Apr 2021