Search results for "Highlights"
Studies examine prescribing patterns, access issues with newer diabetes drug classes
Use of tirzepatide, glucagon-like peptide-1 receptor agonists, and sodium-glucose cotransporter-2 inhibitors increased sharply in the U.S. from 2021 to 2023, one study found, while another noted inequities in availability of newer medications for type 2 diabetes.
https://diabetes.acponline.org/archives/2025/05/09/3.htm
9 May 2025
Standard care noninferior to acellular, cellular matrix products for diabetic foot ulcers
Researchers found no clinically significant differences in ulcer healing between the treatment types but found that acellular matrix products were more cost-effective than cellular matrix products and should thus be considered if standard care fails.
https://diabetes.acponline.org/archives/2025/05/09/2.htm
9 May 2025
Alternative measures didn't help in conditions thought to affect accuracy of HbA1c level
Using fructosamine or glycated albumin did not improve overall accuracy of glycemic measurement in an African population overall or in patients with sickle cell trait, anemia, or renal impairment, according to a comparison of these measures with HbA1c level and continuous glucose monitoring.
https://diabetes.acponline.org/archives/2025/05/09/1.htm
9 May 2025
Gastric bypass increased diabetes remission versus sleeve gastrectomy, small trial finds
At five years after gastric bypass, half of patients with type 2 diabetes and obesity had an HbA1c level less than 6%, compared to 20% of those randomized to sleeve gastrectomy, according to a secondary analysis of a Norwegian trial.
https://diabetes.acponline.org/archives/2025/04/11/3.htm
11 Apr 2025
Switching to tirzepatide improves outcomes vs. escalating dulaglutide in type 2 diabetes
An industry-funded randomized trial found that switching to tirzepatide after inadequate response to dulaglutide led to significant additional reductions in HbA1c levels and weight at 40 weeks compared with increasing the dulaglutide dose.
https://diabetes.acponline.org/archives/2025/04/11/2.htm
11 Apr 2025
Older patients have increased hypoglycemia risk soon after beta-blocker initiation
Hypoglycemia risk nearly doubled in the immediate period after initiation of beta-blockers compared with long-standing use, and the risk was higher in patients who were also taking insulin, a Canadian study of older patients with type 2 diabetes found.
https://diabetes.acponline.org/archives/2025/04/11/1.htm
11 Apr 2025
Studies show potential sequelae on diabetic eye from cataract surgery, GLP-1 use
One retrospective study found that progression to proliferative diabetic retinopathy was more likely after cataract surgery, while another showed that a modest increase in the risk of nonarteritic anterior ischemic optic neuropathy may be associated with the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide.
https://diabetes.acponline.org/archives/2025/03/14/3.htm
14 Mar 2025
One-hour glucose tolerance test accurate, convenient for postpartum assessment
The one-hour test identified dysglycemia in 60 of 70 patients who were also diagnosed by their two-hour glucose value, as well as 96 additional patients, a single-center Canadian study found.
https://diabetes.acponline.org/archives/2025/03/14/2.htm
14 Mar 2025
Model could help select initial glucose-lowering therapy for type 2 diabetes
Age, duration of diabetes, sex, baseline body mass index, and baseline levels of HbA1c, estimated glomerular filtration rate, cholesterol levels, and alanine aminotransferase were used to predict the effectiveness of five classes of diabetes drugs.
https://diabetes.acponline.org/archives/2025/03/14/1.htm
14 Mar 2025
SGLT-2 inhibitors, GLP-1 receptor agonists lower COPD exacerbation risk
Sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists were associated with significant reductions in severe chronic obstructive pulmonary disease (COPD) exacerbations compared with dipeptidyl peptidase-4 inhibitors, an observational study found.
https://diabetes.acponline.org/archives/2025/02/14/3.htm
14 Feb 2025
Micronutrient deficiencies, especially vitamin D, common in type 2 diabetes
Approximately 45% of patients with type 2 diabetes were deficient in multiple micronutrients, with vitamin D deficiency the most common at approximately 61%, a meta-analysis of 132 studies found.
https://diabetes.acponline.org/archives/2025/02/14/2.htm
14 Feb 2025
GLP-1 receptor agonists show effects on substance disorders, infections
Researchers should examine the effects of glucagon-like peptide 1 (GLP-1) receptor agonists on multiple diseases, according to the authors of a systematic review that looked at 175 health outcomes in patients taking diabetes medications.
https://diabetes.acponline.org/archives/2025/02/14/1.htm
14 Feb 2025
U.K. consensus statement targets potential barriers to CGM use
Primary care teams face a critical need for education, training, and resources such as electronic health record integration to increase use of continuous glucose monitoring (CGM) in type 2 diabetes, an industry-funded consensus statement said.
https://diabetes.acponline.org/archives/2025/01/10/3.htm
10 Jan 2025
Trial supports insulin as first-line treatment for gestational diabetes
Metformin plus glyburide as needed did not meet criteria for noninferiority to insulin on the outcome of the proportion of infants born large for gestational age, a multicenter trial of 820 patients in the Netherlands found.
https://diabetes.acponline.org/archives/2025/01/10/2.htm
10 Jan 2025
ADA releases updated Standards of Care for 2025
The American Diabetes Association (ADA) has added new recommendations on screening for type 1 diabetes, referring for dental care, and addressing female sexual dysfunction, among other topics.
https://diabetes.acponline.org/archives/2025/01/10/1.htm
10 Jan 2025
Inhaled insulin noninferior to usual care, industry trial in type 1 diabetes finds
Patients who began using inhaled insulin were more likely to have an improvement or worsening in their HbA1c level than patients who continued their existing insulin regimens, but overall glycemic control was similar with either strategy, a randomized trial found.
https://diabetes.acponline.org/archives/2024/12/13/3.htm
13 Dec 2024
Hypoglycemic events linked to subsequent stroke risk in diabetes
Medicare patients with diabetes who had a hypoglycemic event had higher odds of a subsequent acute ischemic stroke. Risk was highest on the day after the event and decreased with time but persisted for 30 days, the case-crossover study found.
https://diabetes.acponline.org/archives/2024/12/13/2.htm
13 Dec 2024
Diabetes rates hold steady in latest U.S. report, rising around the world
In the U.S., 11.3% of adults have diagnosed diabetes and 4.5% have undiagnosed diabetes, a CDC report found. A global analysis found that diabetes rates are rising fastest in low- and middle-income countries in southeast Asia, south Asia, the Middle East and north Africa, and Latin America and the Caribbean.
https://diabetes.acponline.org/archives/2024/12/13/1.htm
13 Dec 2024
Review calls for increased measurement, treatment of diabetes distress
An analysis of six studies found that an average of 78.3% of people with diabetes had at least some clinically relevant diabetes distress-related problems and that a commonly used scale does not capture most patients with distress.
https://diabetes.acponline.org/archives/2024/11/08/3.htm
8 Nov 2024
Dexamethasone not associated with survival benefit in inpatients with COVID-19, diabetes
Patients with diabetes and severe COVID-19 who were treated with dexamethasone had slower time to clinical recovery than propensity-matched patients who didn't get dexamethasone, and steroid treatment did not improve mortality, a retrospective study found.
https://diabetes.acponline.org/archives/2024/11/08/2.htm
8 Nov 2024