Case report of insulin autoimmune syndrome
A recently published case described a patient with type 2 diabetes treated with metformin who had recurrent spontaneous hypoglycemia.
A recent case described a 79-year-old woman with type 2 diabetes, treated with metformin, and recurrent spontaneous hypoglycemia characterized by low plasma glucose, inappropriately elevated plasma C-peptide and insulin levels, and the presence of antibodies against endogenous insulin. The case was published by Annals of Internal Medicine: Clinical Cases on July 2. The patient was diagnosed with insulin autoimmune syndrome, or Hirata disease, and it was attributed to previous treatment with an oral supplement containing alpha-lipoic acid.