Early mobilization associated with worse outcomes in ICU patients with diabetes
Patients with diabetes in the ICU who received minimized sedation and early physiotherapy were at higher risk for death at 180 days than those who did not, a recent study found.
ICU patients with diabetes did not benefit and potentially experienced harmful effects from early mobilization, according to a recent study.
Researchers performed a post hoc analysis of a randomized multicountry multicenter trial to assess whether diabetes modified the relationship between early mobilization in the ICU and clinical outcomes, published May 19 by the American Journal of Respiratory and Critical Care Medicine.
The study found that patients with diabetes had fewer days alive and out of hospital at day 180 and a higher 180-day mortality rate versus those without diabetes. Among patients who received early mobilization, those with diabetes had a median of 73.0 days alive and out of hospital at day 180 while those without had a median of 146.5, a nonstatistically significant difference. However, early mobilization was associated with higher odds of death at 180 days in patients with diabetes (adjusted odds ratio, 3.47 [95% CI, 1.67 to 7.61]; P=0.001 for the interaction).
A full summary of the study is available in ACP Hospitalist, a publication exclusive to ACP members. Single sign-on is required.