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Younger age at type 2 diabetes onset linked to higher risk of subsequent dementia

An analysis of a prospective cohort study in the U.K. found that developing type 2 diabetes before age 70 years was associated with greater likelihood of having dementia, and dementia risk increased with longer duration of diabetes.
https://diabetes.acponline.org/archives/2021/05/14/3.htm
14 May 2021

Depression associated with death in older patients with type 2 diabetes

A study that screened patients with type 2 diabetes in Spain for depression found that depression was associated with higher all-cause mortality in patients older than age 65 years, but not in younger patients.
https://diabetes.acponline.org/archives/2021/06/11/2.htm
11 Jun 2021

SGLT-2 inhibitors associated with increased risk for diabetic ketoacidosis

A cohort study found a threefold increase in the risk for diabetic ketoacidosis with sodium-glucose cotransporter-2 (SGLT-2) inhibitors compared to dipeptidyl peptidase-4 (DPP-4) inhibitors, with possible variation by severity or duration of diabetes.
https://diabetes.acponline.org/archives/2020/08/14/2.htm
14 Aug 2020

DPP-4 inhibitors associated with risk of cholecystitis, meta-analysis finds

Patients with type 2 diabetes who were randomized to receive dipeptidyl peptidase-4 (DPP-4) inhibitors had higher rates of gallbladder disease than those who got placebo or nonincretin drugs, but no difference in risk of cholelithiasis or biliary diseases.
https://diabetes.acponline.org/archives/2022/07/08/1.htm
8 Jul 2022

Program directs stable diabetes patients from endocrinology back to primary care

One academic health system developed a program to “graduate” patients out of endocrinology visits for their diabetes. Criteria included HbA1c level less than 8.0%, blood pressure less than 140/90 mm Hg, no tobacco use, and use of statins and aspirin if needed.
https://diabetes.acponline.org/archives/2022/09/16/1.htm
16 Sep 2022

AHA issues policy statement on reducing lower-extremity amputations

Amputations among U.S. patients with diabetes decreased between 2000 and 2009 but increased by 50% from 2009 to 2015, leading the American Heart Association (AHA) to call for better identification and treatment of peripheral artery disease and propose policy solutions.
https://diabetes.acponline.org/archives/2021/04/09/3.htm
9 Apr 2021

CGM improves glucose control in high-risk groups with type 1 diabetes, studies find

Continuous glucose monitoring (CGM) was associated with improved HbA1c levels among adolescents and young adults in one trial and less hypoglycemia among older adults in another.
https://diabetes.acponline.org/archives/2020/07/10/2.htm
10 Jul 2020

Moderating carbohydrates associated with lower mortality rates in type 2 diabetes

An observational study based on U.S. data compared hazard ratios for death based on overall, unhealthy, and healthy low-carb diet scores according to percentage of energy obtained from total and subtypes of carbohydrate, protein, and fat.
https://diabetes.acponline.org/archives/2022/05/13/1.htm
13 May 2022

KDIGO made 12 recommendations for managing diabetes with CKD

The kidney group's guideline supports metformin and sodium–glucose cotransporter-2 inhibitors as first-line therapies for patients with chronic kidney disease (CKD) based on consistent trial data showing their effectiveness, noted an ACP Journal Club commentary.
https://diabetes.acponline.org/archives/2021/03/12/6.htm
12 Mar 2021

Exercise and CBT are cost-effective for diabetes patients with depression

A study used simulation modeling to project the long-term effects of a three-month exercise and cognitive behavioral therapy (CBT) intervention for patients with type 2 diabetes and major depressive disorder. It found clear cost-effectiveness with the interventions alone or combined.
https://diabetes.acponline.org/archives/2021/03/12/3.htm
12 Mar 2021

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