Intensive treatment was defined as use of more glucose-lowering medications than recommended by practice guidelines and was found in 18.7% of clinically complex Medicare patients.
The U.K.-based retrospective cohort study used a database that linked national hospitalization and mortality data for people who were prescribed second-line regimens after metformin.
Excess mortality associated with diabetes was highest in patients younger than age 75 who had had diabetes for a longer time period, with the relative hazard highest in women, a study found.
A 1-hour glucose value above 155 mg/dL predicted mortality even when the 2-hour glucose value was below 140 mg/dL, according to the 33-year study.
The results of this study pose the question of whether the increased likelihood of bladder cancer, which is rare, justifies withholding pioglitazone from adults with type 2 diabetes, according to an accompanying editorial.
Despite increasing adoption of insulin pumps and continuous glucose monitors, control of HbA1c hasn't necessarily improved, the authors noted.
Researchers studied an early intervention model in which an inpatient diabetes team electronically identified patients with hyperglycemia and aimed to provide bedside management within 24 hours of admission, compared with a referral-based
not determine causality between insulin and mortality, we highlight a vulnerable population which needs additional resources in the discharge transition period,” the authors wrote.“ Further inquiry should determine appropriate interventions to
Patients with type 1 diabetes and a mean three-year HbA1c level greater than 8.0% had a higher fracture risk than those with a mean three-year HbA1c level of 7.0% or less.
British patients with type 1 diabetes were enrolled in group training courses that taught flexible intensive insulin treatment and then randomized to an insulin pump or multiple daily injections and followed for two years.