Search results for "Highlights"
Finerenone works by quickly lowering albuminuria, analysis finds
Reductions in the urine albumin-to-creatinine ratio within four months were responsible for 84% of the treatment effect of finerenone on kidney outcomes and 37% of that on cardiovascular outcomes, according to an industry-funded four-year analysis of trials in patients with chronic kidney disease and type 2 diabetes.
https://diabetes.acponline.org/archives/2023/12/08/6.htm
8 Dec 2023
In patients with type 2 diabetes or HF, SGLT2 inhibitors reduce gout-related outcomes
The effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on gout in patients with type 2 diabetes or heart failure (HF) may allow reduced polypharmacy when treatment for gout is also needed, an ACP Journal Club commentary said.
https://diabetes.acponline.org/archives/2023/11/10/6.htm
10 Nov 2023
Spotlight on diabetes drug class comparisons
A large trial compared insulin, a sulfonylurea, a glucagon-like peptide-1 (GLP-1) receptor agonist, and a dipeptidyl peptidase-4 inhibitor as second-line therapy, while a modeling study considered GLP-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors as first-line agents.
https://diabetes.acponline.org/archives/2022/10/14/5.htm
14 Oct 2022
High-normal albumin-to-creatinine ratio associated with CV events in type 2 diabetes
Patients with an elevated urinary albumin-to-creatinine ratio, even below 30 mg/g, were at increased risk for major adverse cardiovascular (CV) events, a post hoc analysis of the ACCORD trial found.
https://diabetes.acponline.org/archives/2023/11/10/3.htm
10 Nov 2023
Women more likely to have pain with diabetic peripheral neuropathy
Cardiometabolic factors traditionally associated with microvascular disease were not associated with risk for painful diabetic peripheral neuropathy in patients with type 1 diabetes, a European study found.
https://diabetes.acponline.org/archives/2023/11/10/2.htm
10 Nov 2023
Higher aspirin dose no more effective for CV prevention in high-risk patients with diabetes
A subgroup analysis of a randomized trial found that patients with diabetes and atherosclerotic cardiovascular (CV) disease had similar outcomes whether they took 81 mg or 325 mg of aspirin daily.
https://diabetes.acponline.org/archives/2023/10/13/10.htm
13 Oct 2023
Younger, leaner patients may have undiagnosed type 2 diabetes, study finds
An analysis of 56 national health surveys throughout the world found that a substantial proportion of patients with a fasting plasma glucose level of 126 mg/dL (7.0 mmol/L) or greater may be younger than age 35 years and/or be in the underweight or normal weight category.
https://diabetes.acponline.org/archives/2023/07/14/3.htm
14 Jul 2023
Young adults' lack of regular diabetes care may be linked to beliefs about medication
Follow-up research from the TODAY study found that a quarter of participants, ages 19 to 31 years, lacked a usual place for diabetes care and almost half had an urgent care visit in the past year. Belief in the necessity of medications was associated with regular access to care.
https://diabetes.acponline.org/archives/2023/08/11/2.htm
11 Aug 2023
Monofilament test for diagnosing diabetic polyneuropathy has high rate of false negatives
A Norwegian study found that the 5.07/10-g monofilament test was less sensitive in women and in older patients and less specific in patients with neuropathic pain. The study's authors recommended against using the monofilament test to diagnose diabetic polyneuropathy.
https://diabetes.acponline.org/archives/2023/12/08/1.htm
8 Dec 2023
Liraglutide shows some benefits as adjunctive therapy in type 1 diabetes, review finds
A systematic review and meta-analysis of studies involving four glucagon-like peptide-1 receptor agonists found that liraglutide had the greatest effect on HbA1c level, weight, and total insulin dose, although odds of nausea and ketosis were higher.
https://diabetes.acponline.org/archives/2023/09/08/2.htm
8 Sep 2023