Search results for "Highlights"


 
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SGLT2 inhibitors, GLP-1 agonists associated with lower mortality compared to DPP-4 inhibitors, analysis finds

Glucagon-like peptide-1 (GLP-1) agonists were associated with a higher risk of adverse events than sodium-glucose cotransporter-2 (SGLT2) inhibitors or dipeptidyl peptidase 4 (DPP-4) inhibitors, according to the meta-analysis.
https://diabetes.acponline.org/archives/2018/05/11/1.htm
11 May 2018

Systolic BP variability associated with increased risk of death, CV events in patients with type 2 diabetes, meta-analysis finds

While current guidelines use only the absolute value of blood pressure (BP) to stratify a patient's cardiovascular (CV) risk, the results suggest that variability in systolic BP may also contribute to risk stratification in this high-risk population, the authors concluded.
https://diabetes.acponline.org/archives/2019/07/12/1.htm
12 Jul 2019

Cardiovascular benefits of adding ezetimibe to statin therapy may be greater in patients with diabetes, study finds

Participants were randomized to receive either ezetimibe or placebo in addition to background simvastatin, and the subgroup of patients with diabetes was compared to those without the disease.
https://diabetes.acponline.org/archives/2018/01/12/2.htm
12 Jan 2018

Cardiovascular event rates similar between once-weekly exenatide and placebo in patients with type 2 diabetes

A limitation of the industry-funded randomized trial was the high rate of early discontinuation: 43.0% of patients on exenatide and 45.2% of those on placebo.
https://diabetes.acponline.org/archives/2017/10/13/1.htm
13 Oct 2017

Expert panel recommends target ranges for continuous glucose monitoring data

Adults with type 1 and type 2 diabetes should aim to spend more than 70% of each day in the target range of 70 to 180 mg/dL (3.9 to 10.0 mmol/L), which corresponds to an HbA1c level of about 7%, the consensus report said.
https://diabetes.acponline.org/archives/2019/06/14/1.htm
14 Jun 2019

Metformin associated with B-vitamin deficiency, cognitive dysfunction in older patients

This observational study suggests that metformin use in hyperglycemic older patients is associated with vitamin B12 and B6 (pyridoxine) deficiency and poorer cognitive performance.
https://diabetes.acponline.org/archives/2019/04/05/1.htm
5 Apr 2019

Sociodemographic, clinical factors may influence insulin initiation in type 2 diabetes

The researchers found an inverse association between insulin initiation and age, and black and Hispanic participants were less likely to have insulin initiated compared with white participants.
https://diabetes.acponline.org/archives/2018/02/09/3.htm
9 Feb 2018

Intensive BP control associated with worse CV outcomes in type 2 diabetes and recent ACS

A post hoc analysis found that patients with baseline systolic blood pressure (BP) <120 mm Hg or >160 mm Hg or follow-up BP <130 mm Hg had a significantly increased risk for a composite outcome of death from cardiovascular (CV) causes, nonfatal myocardial infarction, and nonfatal stroke.
https://diabetes.acponline.org/archives/2018/11/09/1.htm
9 Nov 2018

Benefits of gastric bypass may diminish after 5 years

Patients with type 2 diabetes who had Roux-en-Y gastric bypass surgery maintained significant, although shrinking, improvements in HbA1c compared to those receiving lifestyle and medical management.
https://diabetes.acponline.org/archives/2018/02/09/2.htm
9 Feb 2018

Diabetes treatment in the elderly has improved, but complex regimens still common, study finds

Between 2007 and 2014, more Medicare beneficiaries were newly prescribed metformin, dipeptidyl peptidase-4 inhibitors, and sodium-glucose cotransporter 2 inhibitors, while fewer received long-acting sulfonylureas or thiazolidinediones.
https://diabetes.acponline.org/archives/2018/03/09/3.htm
9 Mar 2018

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