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Spotlight on depression in diabetes

Recent studies analyzed depression in diabetes, including associated causes of death, the potential benefits of peer support and a plant-based diet, and strategies for screening and treatment.
https://diabetes.acponline.org/archives/2018/11/09/5.htm
9 Nov 2018

Intensive glucose control soon after diagnosis may improve diabetes outcomes, study indicates

The findings underscore the urgency of early diagnosis of diabetes and the consequences of failing to achieve near-normal glycemia soon after patients are diagnosed, according to the study authors.
https://diabetes.acponline.org/archives/2018/09/14/2.htm
14 Sep 2018

SGLT2 inhibitors associated with increased risk of amputations, diabetic ketoacidosis

Sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists had similar rates of other adverse events, including bone fracture, acute kidney injury, serious urinary tract infection, venous thromboembolism, and acute pancreatitis.
https://diabetes.acponline.org/archives/2018/12/14/3.htm
14 Dec 2018

Hypoglycemia may be associated with myocardial damage

Among patients with coronary artery disease, severity and frequency of hypoglycemia were associated with increased levels of high-sensitivity cardiac troponin T, although the association was attenuated in adjusted analyses.
https://diabetes.acponline.org/archives/2018/10/12/3.htm
12 Oct 2018

Diabetes patients without other risk factors may have near-normal mortality risks

The studied risk factors were HbA1c level, LDL cholesterol level, presence of albuminuria, smoking status, and blood pressure.
https://diabetes.acponline.org/archives/2018/09/14/3.htm
14 Sep 2018

Mortality benefit of tighter glycemic control may vary by diabetes duration, study finds

Mortality risk increased with worse glycemic control among patients who had had diabetes for less than five years, while a mean HbA1c level between 6.5% to 7.9% was associated with the lowest mortality risk in those who had had the disease longer.
https://diabetes.acponline.org/archives/2019/11/08/1.htm
8 Nov 2019

Integrated care model offers noninferior diabetes care to gold-standard specialist clinics

A study conducted in Australia found that general practitioners with specialization in diabetes care and subspecialist-led clinics reduced HbA1c levels by similar amounts in patients with complex type 2 diabetes.
https://diabetes.acponline.org/archives/2018/10/12/4.htm
12 Oct 2018

Metformin associated with fewer cardiovascular events than sulfonylureas after decline in kidney function

The findings from this retrospective study further support metformin as the first-line treatment to which other diabetes medications are added, even in patients who are in the early stages of chronic kidney disease, an editorial noted.
https://diabetes.acponline.org/archives/2019/10/11/1.htm
11 Oct 2019

Preoperative glucose levels may predict postoperative cardiac outcomes regardless of whether patients have diabetes

For patients without diabetes, predictors of myocardial injury after noncardiac surgery included a casual glucose level of more than 6.86 mmol/L (124 mg/dL) and a fasting glucose level of more than 6.41 mmol/L (116 mg/dL).
https://diabetes.acponline.org/archives/2018/08/10/3.htm
10 Aug 2018

Intermittent fasting appears effective for HbA1c reduction in type 2 diabetes

Patients on the intermittent energy restriction diet ate 500 to 600 kcal/d on two nonconsecutive days each week and followed their usual diet on the other days. They were compared to a group eating 1,200 to 1,500 kcal/d.
https://diabetes.acponline.org/archives/2018/08/10/2.htm
10 Aug 2018

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