Search results for "Highlights"
Finerenone works by quickly lowering albuminuria, analysis finds
Reductions in the urine albumin-to-creatinine ratio within four months were responsible for 84% of the treatment effect of finerenone on kidney outcomes and 37% of that on cardiovascular outcomes, according to an industry-funded four-year analysis of trials in patients with chronic kidney disease and type 2 diabetes.
https://diabetes.acponline.org/archives/2023/12/08/6.htm
8 Dec 2023
Baricitinib may preserve beta-cell function in early stages of type 1 diabetes
An editorial noted that increasing knowledge developed from trials of patients with early type 1 diabetes could eventually enable treatment to prevent clinical disease.
https://diabetes.acponline.org/archives/2023/12/08/2.htm
8 Dec 2023
CGM use linked with modest HbA1c decreases in patients with type 2 diabetes
Real-time continuous glucose monitoring (CGM) increased the percent of time in range among patients with type 2 diabetes compared with self-monitoring, and both real-time and flash CGM lowered HbA1c levels, a meta-analysis found.
https://diabetes.acponline.org/archives/2023/12/08/3.htm
8 Dec 2023
Monofilament test for diagnosing diabetic polyneuropathy has high rate of false negatives
A Norwegian study found that the 5.07/10-g monofilament test was less sensitive in women and in older patients and less specific in patients with neuropathic pain. The study's authors recommended against using the monofilament test to diagnose diabetic polyneuropathy.
https://diabetes.acponline.org/archives/2023/12/08/1.htm
8 Dec 2023
Women more likely to have pain with diabetic peripheral neuropathy
Cardiometabolic factors traditionally associated with microvascular disease were not associated with risk for painful diabetic peripheral neuropathy in patients with type 1 diabetes, a European study found.
https://diabetes.acponline.org/archives/2023/11/10/2.htm
10 Nov 2023
In patients with type 2 diabetes or HF, SGLT2 inhibitors reduce gout-related outcomes
The effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on gout in patients with type 2 diabetes or heart failure (HF) may allow reduced polypharmacy when treatment for gout is also needed, an ACP Journal Club commentary said.
https://diabetes.acponline.org/archives/2023/11/10/6.htm
10 Nov 2023
High-normal albumin-to-creatinine ratio associated with CV events in type 2 diabetes
Patients with an elevated urinary albumin-to-creatinine ratio, even below 30 mg/g, were at increased risk for major adverse cardiovascular (CV) events, a post hoc analysis of the ACCORD trial found.
https://diabetes.acponline.org/archives/2023/11/10/3.htm
10 Nov 2023
Diabetes patients lost more weight with time-restricted eating than calorie counting
Over the course of six months, eating only between noon and 8 p.m. had a greater impact on weight loss and a similar effect on HbA1c levels compared with reducing energy intake by 25%, according to a small randomized trial of patients with type 2 diabetes and obesity.
https://diabetes.acponline.org/archives/2023/11/10/1.htm
10 Nov 2023
Higher aspirin dose no more effective for CV prevention in high-risk patients with diabetes
A subgroup analysis of a randomized trial found that patients with diabetes and atherosclerotic cardiovascular (CV) disease had similar outcomes whether they took 81 mg or 325 mg of aspirin daily.
https://diabetes.acponline.org/archives/2023/10/13/10.htm
13 Oct 2023
COVID-19 boosters associated with transient increases in glycemia, study finds
A small cohort study of patients with type 1 diabetes who received COVID-19 booster vaccines found significant increases in their blood glucose levels on the second and third day after vaccination.
https://diabetes.acponline.org/archives/2023/10/13/3.htm
13 Oct 2023