Search results for "Highlights"

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Severe insulin-resistant diabetes associated with better metabolic surgery outcomes

Patients with severe insulin-resistant diabetes had better outcomes after metabolic surgery than those with mild obesity-related diabetes or severe insulin-deficient diabetes, both in terms of type 2 diabetes remission and renal function, with no additional surgical risk.
11 Mar 2022

Interventions uncommon for prediabetes in primary care

A U.S. retrospective study found that while 63.4% of prediabetes patients had repeated glycemic testing over one year of follow-up, 10.4% had a primary care visit with a coded diagnosis of prediabetes, 1.0% were referred for nutrition services, and 5.4% were prescribed metformin.
11 Mar 2022

Association of inflammation with mortality in COVID-19 didn't differ by diabetes status

A single-center, case-control study of patients who were hospitalized with COVID-19 found a link between elevated levels of IL-6, IL-8, and interferon-γ-induced protein 10 and mortality risk, regardless of whether patients had type 2 diabetes.
14 Jan 2022

Nearly one-third of patients were nonadherent to newly prescribed SGLT-2 inhibitors, GLP-1 receptor agonists

Factors associated with not filling a new prescription for a sodium-glucose cotransporter-2 (SGLT-2) inhibitor or a glucagon-like peptide-1 (GLP-1) receptor agonist included older age, Black race, male sex, certain comorbid conditions, and having a primary care clinician prescribe the drug, a study found.
11 Feb 2022

Obesity increasing in type 1 diabetes, associated with higher risk for chronic kidney disease

Obesity in type 1 diabetes rose from 2004 to 2018, and patients with type 1 had a higher adjusted prevalence of low estimated glomerular filtration rate and albuminuria than those with type 2, an analysis of one health system found.
11 Feb 2022

Metformin use during pregnancy not associated with adverse outcomes in children

A industry-conducted cohort study in Finland found that childhood obesity, hypoglycemia, hyperglycemia, diabetes, and challenges in motor-social development did not appear to be associated with in utero exposure to metformin or metformin and insulin versus insulin alone.
14 Jan 2022

Study finds long-term reductions in cardiovascular risk factors with SGLT-2 inhibitors

While the meta-analysis also found durable reductions in macrovascular complications and mortality with sodium-glucose cotransporter-2 (SGLT-2) inhibitors versus placebo, there were insufficient data comparing the drug class to other antihyperglycemic medications.
10 Dec 2021

Adults with diabetes more likely to report mental stress during the COVID-19 pandemic

An online survey of U.S. adults in mid-2020, most of whom were White women, found that those with diabetes were less likely to report resilience and more likely to experience depression than adults without diabetes.
10 Dec 2021

No differences seen in outcomes with one-step vs. two-step gestational diabetes screening

The one-step screening process, which used a two-hour fasting glucose tolerance test, found more cases of gestational diabetes in a randomized trial, but perinatal and maternal complications did not differ.
12 Mar 2021

Choice of SGLT-2 inhibitors, GLP-1 receptor agonists should be based on individual risk

A meta-analysis comparing sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists found differing effects, including that the SGLT-2 inhibitors affected heart failure outcomes while GLP-1 receptor agonists reduced stroke risk.
12 Feb 2021

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