Search results for "Highlights"
Liraglutide had best outcomes in trial of second-line therapies added to metformin
Patients randomized to liraglutide had a 60.3% risk of reaching a composite outcome of glycemic deterioration, weight gain, or hypoglycemia compared with 81.4% on glimepiride, 71.9% on glargine, and 69.6% on sitagliptin.
https://diabetes.acponline.org/archives/2024/02/09/1.htm
9 Feb 2024
Finerenone works by quickly lowering albuminuria, analysis finds
Reductions in the urine albumin-to-creatinine ratio within four months were responsible for 84% of the treatment effect of finerenone on kidney outcomes and 37% of that on cardiovascular outcomes, according to an industry-funded four-year analysis of trials in patients with chronic kidney disease and type 2 diabetes.
https://diabetes.acponline.org/archives/2023/12/08/6.htm
8 Dec 2023
Baricitinib may preserve beta-cell function in early stages of type 1 diabetes
An editorial noted that increasing knowledge developed from trials of patients with early type 1 diabetes could eventually enable treatment to prevent clinical disease.
https://diabetes.acponline.org/archives/2023/12/08/2.htm
8 Dec 2023
CGM use linked with modest HbA1c decreases in patients with type 2 diabetes
Real-time continuous glucose monitoring (CGM) increased the percent of time in range among patients with type 2 diabetes compared with self-monitoring, and both real-time and flash CGM lowered HbA1c levels, a meta-analysis found.
https://diabetes.acponline.org/archives/2023/12/08/3.htm
8 Dec 2023
Physical activity may weaken association between cognitive decline and diabetes
Diabetes increased risk for cognitive impairment among inactive but not active adults in a cohort study in Brazil, and active adults with diabetes developed cognitive impairment 2.73 years later, on average, than the inactive diabetes patients.
https://diabetes.acponline.org/archives/2024/01/12/1.htm
12 Jan 2024
Women more likely to have pain with diabetic peripheral neuropathy
Cardiometabolic factors traditionally associated with microvascular disease were not associated with risk for painful diabetic peripheral neuropathy in patients with type 1 diabetes, a European study found.
https://diabetes.acponline.org/archives/2023/11/10/2.htm
10 Nov 2023
In patients with type 2 diabetes or HF, SGLT2 inhibitors reduce gout-related outcomes
The effects of sodium-glucose cotransporter 2 (SGLT2) inhibitors on gout in patients with type 2 diabetes or heart failure (HF) may allow reduced polypharmacy when treatment for gout is also needed, an ACP Journal Club commentary said.
https://diabetes.acponline.org/archives/2023/11/10/6.htm
10 Nov 2023
High-normal albumin-to-creatinine ratio associated with CV events in type 2 diabetes
Patients with an elevated urinary albumin-to-creatinine ratio, even below 30 mg/g, were at increased risk for major adverse cardiovascular (CV) events, a post hoc analysis of the ACCORD trial found.
https://diabetes.acponline.org/archives/2023/11/10/3.htm
10 Nov 2023
Monofilament test for diagnosing diabetic polyneuropathy has high rate of false negatives
A Norwegian study found that the 5.07/10-g monofilament test was less sensitive in women and in older patients and less specific in patients with neuropathic pain. The study's authors recommended against using the monofilament test to diagnose diabetic polyneuropathy.
https://diabetes.acponline.org/archives/2023/12/08/1.htm
8 Dec 2023
Update in Endocrinology highlights top diabetes research of 2013
Ten studies from 2013 with potential to change endocrinology practice were summarized in Annals of Internal Medicine's annual Update in Endocrinology, published in the June 3 issue.
https://diabetes.acponline.org/archives/2014/06/13/5.htm
13 Jun 2014