Intense multifactorial intervention associated with increased life span, time to CVD events in type 2 diabetes
The intensive intervention was initially conducted for a median of 7.8 years and used both pharmacologic and behavioral methods to target coexisting risk factors for late complications of diabetes.
Elevations in high-sensitivity troponin T or N-terminal pro-B-type natriuretic peptide were significantly associated with risk of cardiovascular death, myocardial infarction, and hospitalization for heart failure, while C-reactive protein was a less
Patients with type 2 diabetes and a systolic blood pressure of 110 to 119 mm Hg appeared to have a lower risk of cardiovascular disease than patients who had systolic blood pressures of 130 to 139 mm Hg, according to a registry study.
The study looked at data from the Sweden National Diabetes Register to determine what patient characteristics were related to all-cause mortality or death from cardiovascular-, diabetes-, or cancer-related causes.
Intensive treatment was defined as use of more glucose-lowering medications than recommended by practice guidelines and was found in 18.7% of clinically complex Medicare patients.
The U.K.-based retrospective cohort study used a database that linked national hospitalization and mortality data for people who were prescribed second-line regimens after metformin.
Excess mortality associated with diabetes was highest in patients younger than age 75 who had had diabetes for a longer time period, with the relative hazard highest in women, a study found.
A 1-hour glucose value above 155 mg/dL predicted mortality even when the 2-hour glucose value was below 140 mg/dL, according to the 33-year study.
The results of this study pose the question of whether the increased likelihood of bladder cancer, which is rare, justifies withholding pioglitazone from adults with type 2 diabetes, according to an accompanying editorial.
Some other new or revised recommendations include the following:. The ADA updated the nutrition section to highlight the importance of weight loss in patients at high risk and added recommendations on